Alternative splicing as a source of phenotypic diversity

CJ Wright, CWJ Smith, CD Jiggins - Nature Reviews Genetics, 2022 - nature.com
A major goal of evolutionary genetics is to understand the genetic processes that give rise to
phenotypic diversity in multicellular organisms. Alternative splicing generates multiple …

The role of alternative splicing in adaptation and evolution

JP Verta, A Jacobs - Trends in Ecology & Evolution, 2022 - cell.com
Regulation of gene expression plays a central role in adaptive divergence and evolution.
Although the role of gene regulation in microevolutionary processes is gaining wide …

A high-resolution single-molecule sequencing-based Arabidopsis transcriptome using novel methods of Iso-seq analysis

R Zhang, R Kuo, M Coulter, CPG Calixto, JC Entizne… - Genome biology, 2022 - Springer
Background Accurate and comprehensive annotation of transcript sequences is essential for
transcript quantification and differential gene and transcript expression analysis. Single …

ZmPP2C26 Alternative Splicing Variants Negatively Regulate Drought Tolerance in Maize

F Lu, W Li, Y Peng, Y Cao, J Qu, F Sun… - Frontiers in plant …, 2022 - frontiersin.org
Serine/threonine protein phosphatase 2C (PP2C) dephosphorylates proteins and plays
crucial roles in plant growth, development, and stress response. In this study, we …

Insplico: effective computational tool for studying splicing order of adjacent introns genome-wide with short and long RNA-seq reads

A Gohr, LP Iñiguez, A Torres-Méndez… - Nucleic Acids …, 2023 - academic.oup.com
Although splicing occurs largely co-transcriptionally, the order by which introns are removed
does not necessarily follow the order in which they are transcribed. Whereas several …

Cotranscriptional RNA processing and modification in plants

S Marquardt, E Petrillo, PA Manavella - The Plant Cell, 2023 - academic.oup.com
The activities of RNA polymerases shape the epigenetic landscape of genomes with
profound consequences for genome integrity and gene expression. A fundamental event …

An mTRAN-mRNA interaction mediates mitochondrial translation initiation in plants

HC Tran, V Schmitt, S Lama, C Wang, A Launay-Avon… - Science, 2023 - science.org
Plant mitochondria represent the largest group of respiring organelles on the planet. Plant
mitochondrial messenger RNAs (mRNAs) lack Shine-Dalgarno-like ribosome-binding sites …

Specialization of the photoreceptor transcriptome by Srrm3-dependent microexons is required for outer segment maintenance and vision

L Ciampi, F Mantica, L López-Blanch… - Proceedings of the …, 2022 - National Acad Sciences
Retinal photoreceptors have a distinct transcriptomic profile compared to other neuronal
subtypes, likely reflecting their unique cellular morphology and function in the detection of …

Global transcriptome analysis of allopolyploidization reveals large-scale repression of the D-subgenome in synthetic hexaploid wheat

A Vasudevan, M Lévesque-Lemay, T Edwards… - Communications …, 2023 - nature.com
Synthetic hexaploid wheat (SHW) lines are created as pre-breeding germplasm to diversify
the D subgenome of hexaploid wheat and capitalize upon the untapped genetic diversity of …

PlantExp: a platform for exploration of gene expression and alternative splicing based on public plant RNA-seq samples

J Liu, Y Zhang, Y Zheng, Y Zhu, Y Shi… - Nucleic Acids …, 2023 - academic.oup.com
Over the last decade, RNA-seq has produced a massive amount of plant transcriptomic
sequencing data deposited in public databases. Reanalysis of these public datasets can …