Radiotherapy is one of the most common countermeasures for treating a wide range of
tumors. However, the radioresistance of cancer cells is still a major limitation for …

Reactive oxygen species (ROS) are by‐products of normal cell activity. They are produced
in many cellular compartments and play a major role in signaling pathways. Overproduction …

Simple Summary The deregulation of the oxidative metabolism in cancer cells,
characterized by an increased ratio between glycolysis and oxygen consumption (Warburgv …

Background and purpose Human hepatocellular carcinoma (HCC) features include
enhanced glycolysis and elevated lactate concentrations. Accumulation of lactate during …

Radiation therapy is one of the major tools of cancer treatment, and is widely used for a
variety of malignant tumours. Radiotherapy causes DNA damage directly by ionization or …

Influential research by Warburg and Cori in the 1920s ignited interest in how cancer cells'
energy generation is different from that of normal cells. They observed high glucose …

Breast cancer (BC) is the most prevalent cancer in women. BC is heterogeneous, with
distinct phenotypical and morphological characteristics. These are based on their gene …

Breast cancer is the most common malignancy in women worldwide and is associated with
high mortality rates despite the continuously advancing treatment strategies. Glucose is …

Canonical WNT/β-catenin signaling is involved in most of the mechanisms that lead to the
formation and development of cancer cells. It plays a central role in three cyclic processes …

Although survival outcomes of cancer patients have been improved dramatically via
conventional chemotherapy and targeted therapy over the last decades, there are still some …