T lymphocytes-related cell network in the pathogenesis of ju... : Current Opinion in
Rheumatology T lymphocytes-related cell network in the pathogenesis of juvenile idiopathic …

Introduction Monocytes are key effector cells in inflammatory processes. We and others have
previously shown that synovial monocytes in childhood-onset arthritis are activated …

Psoriatic arthritis is a chronic debilitating autoimmune condition, and when diagnosed in
patients before the age of eighteen, it is considered pediatric polyarticular juvenile idiopathic …

Biologic and targeted synthetic DMARDs (b/tsDMARDs) have revolutionized the
management of multiple rheumatic inflammatory conditions. Among these, polyarticular JIA …

Objectives Synovial monocytes in oligoarticular juvenile idiopathic arthritis (oJIA) are
polarized, but little is known of how they contribute to disease and attain their pathogenic …

Objectives The main goal of this study was to characterise the frequency and phenotype of
B, T follicular helper (Tfh) and T follicular regulatory (Tfr) cells in peripheral blood and the …

Rheumatoid arthritis (RA) is a complex autoimmune disease characterized by severe joint
inflammation, synovial hyperplasia, and cartilage and bone destruction. Based on our …

Cellular phenotype and function are altered in different microenvironments. For targeted
therapies it is important to understand site-specific cellular adaptations. Juvenile Idiopathic …

Background: Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in
children. Both the humoral and cell mediated immunities are involved in the pathogenesis of …

Despite all the achievements of science and medicine, juvenile idiopathic arthritis today
remains one of the main childhood diseases that lead to severe irreversible consequences …