Biomarkers are detectable molecules that can reflect specific physiological states of cells,
organs, and organisms and therefore be regarded as indicators for specific diseases. And …

Importance Vamorolone is a synthetic steroidal drug with potent anti-inflammatory
properties. Initial open-label, multiple ascending dose-finding studies of vamorolone among …

Vamorolone (AGAMREE®) is an oral, selective, dissociative corticosteroid developed by
ReveraGen BioPharma and Santhera Pharmaceuticals for the treatment of patients with …

Background Treatment with corticosteroids is recommended for Duchenne muscular
dystrophy (DMD) patients to slow the progression of weakness. However, chronic …

New medicines are urgently required to treat the fatal neuromuscular disease Duchenne
muscular dystrophy (DMD). Dimethyl fumarate (DMF) is a potent immunomodulatory small …

Becker muscular dystrophy is caused by mutations in the DMD gene that permit significant
residual dystrophin protein expression in patient muscle. This is in contrast to DMD gene …

Duchenne muscular dystrophy (DMD) is caused by genetic mutations leading to lack of
dystrophin in skeletal muscle. A better understanding of how objective biomarkers for DMD …

Background Duchenne muscular dystrophy (DMD) is a genetic muscle disorder
characterized by progressive muscle wasting associated with persistent inflammation. In this …

Duchenne muscular dystrophy (DMD) is a severe X-linked muscle wasting disease with no
cure. While the precise mechanisms of progressive dystropathology remain unclear …

This commentary provides an independent consideration of data related to the drug
vamorolone (VBP15) as an alternative steroid proposed for treatment of Duchenne muscular …