Determinants of allergenicity

C Traidl-Hoffmann, T Jakob, H Behrendt - Journal of Allergy and Clinical …, 2009 - Elsevier
The question “What makes an allergen an allergen?” has puzzled generations of
researchers, and we still do not have a conclusive answer. Despite increasing knowledge …

Abundance and stability as common properties of allergens

ACY Foo, GA Mueller - Frontiers in Allergy, 2021 - frontiersin.org
There have been many attempts to identify common biophysical properties which
differentiate allergens from their non-immunogenic counterparts. This review will focus on …

The Bet v 1 fold: an ancient, versatile scaffold for binding of large, hydrophobic ligands

C Radauer, P Lackner, H Breiteneder - BMC evolutionary biology, 2008 - Springer
Background The major birch pollen allergen, Bet v 1, is a member of the ubiquitous PR-10
family of plant pathogenesis-related proteins. In recent years, a number of diverse plant …

[HTML][HTML] Do lipids influence the allergic sensitization process?

M Bublin, T Eiwegger, H Breiteneder - Journal of Allergy and Clinical …, 2014 - Elsevier
Allergic sensitization is a multifactorial process that is not only influenced by the allergen
and its biological function per se but also by other small molecular compounds, such as …

Secret of the major birch pollen allergen Bet v 1: identification of the physiological ligand

C Seutter von Loetzen, T Hoffmann, MJ Hartl… - Biochemical …, 2014 - portlandpress.com
The major birch pollen allergen Bet v 1 is the main elicitor of airborne type I allergies and
belongs to the PR-10 family (pathogenesis-related proteins 10). Bet v 1 is the most …

The allergen Bet v 1 in fractions of ambient air deviates from birch pollen counts

JTM Buters, I Weichenmeier, S Ochs, G Pusch… - Allergy, 2010 - Wiley Online Library
To cite this article: Buters JTM, Weichenmeier I, Ochs S, Pusch G, Kreyling W, Boere AJF,
Schober W, Behrendt H. The allergen Bet v 1 in fractions of ambient air deviates from birch …

[HTML][HTML] Crystallographically mapped ligand binding differs in high and low IgE binding isoforms of birch pollen allergen bet v 1

S Kofler, C Asam, U Eckhard, M Wallner… - Journal of molecular …, 2012 - Elsevier
The ability of pathogenesis-related proteins of family 10 to bind a broad spectrum of ligands
is considered to play a key role for their physiological and pathological functions. In …

PR10/Bet v1‐like proteins as novel contributors to plant biochemical diversity

JS Morris, KMP Caldo, S Liang, PJ Facchini - ChemBioChem, 2021 - Wiley Online Library
Pathogenesis‐related (PR) proteins constitute a broad class of plant proteins with
analogues found throughout nature from bacteria to higher eukaryotes. PR proteins were …

Egg white ovalbumin digestion mimicking physiological conditions

G Martos, P Contreras, E Molina… - Journal of Agricultural …, 2010 - ACS Publications
Gastrointestinal digestion of ovalbumin (OVA) was simulated using an in vitro system in two
steps, which mimicked digestion in the stomach and duodenum, to assess the effect of …

RSOsPR10 expression in response to environmental stresses is regulated antagonistically by jasmonate/ethylene and salicylic acid signaling pathways in rice roots

K Takeuchi, A Gyohda, M Tominaga… - Plant and Cell …, 2011 - academic.oup.com
Plant roots play important roles not only in the absorption of water and nutrients, but also in
stress tolerance. Previously, we identified RSOsPR10 as a root-specific pathogenesis …