Children are susceptible to infection with the novel coronavirus SARS-CoV-2. In this time of
uncertainty, this review attempts to compile information that may be helpful to pediatric …

Objectives The manuscript serves as an update on the current management practices for
infantile spasm syndrome (ISS). It includes a detailed summary of the level of current …

Objective To compare the effectiveness of initial treatment for infantile spasms. Methods The
National Infantile Spasms Consortium prospectively followed up children with new-onset …

Circumstances of the COVID-19 pandemic have mandated a change to standard
management of infantile spasms. On April 6, 2020, the Child Neurology Society issued an …

Aim We performed a systematic review and network meta‐analysis (NMA) to obtain
comparative effectiveness estimates and rankings of non‐surgical interventions used to treat …

Objective We aimed to assess the treatment response of infantile‐onset epileptic spasms
(ES) in CDKL5 deficiency disorder (CDD) vs other etiologies. Methods We evaluated …

Aims Prednisone is a corticosteroid-derived drug which is widely used for its role in
immunosuppression and treatment of lung disorders. The current study reports, for the first …

Objective To compare the effectiveness and cost‐effectiveness of adrenocorticotropic
hormone (ACTH) and oral steroids as first‐line treatment for infantile spasm resolution, we …

Background Infantile epileptic spasms syndrome (IESS) is the most common type of severe
epilepsy in infants. However, etiological frequency and optimized therapy, particularly …

Objective This study was undertaken to evaluate our treatment algorithm for infantile
epileptic spasms syndrome (IESS) used between 2000 and 2018. We initiated vigabatrin …