Idiopathic hypercalciuria and formation of calcium renal stones

FL Coe, EM Worcester, AP Evan - Nature Reviews Nephrology, 2016 - nature.com
The most common presentation of nephrolithiasis is idiopathic calcium stones in patients
without systemic disease. Most stones are primarily composed of calcium oxalate and form …

[HTML][HTML] Butyric and citric acids and their salts in poultry nutrition: Effects on gut health and intestinal microbiota

M Melaku, R Zhong, H Han, F Wan, B Yi… - International Journal of …, 2021 - mdpi.com
Intestinal dysfunction of farm animals, such as intestinal inflammation and altered gut
microbiota, is the critical problem affecting animal welfare, performance and farm …

[HTML][HTML] Metabolomics and gene expression analysis reveal down-regulation of the citric acid (TCA) cycle in non-diabetic CKD patients

S Hallan, M Afkarian, LR Zelnick, B Kestenbaum… - …, 2017 - thelancet.com
Chronic kidney disease (CKD) is a public health problem with very high prevalence and
mortality. Yet, there is a paucity of effective treatment options, partly due to insufficient …

Citric acid effects on brain and liver oxidative stress in lipopolysaccharide-treated mice

ME Abdel-SalamOmar, R YounessEman… - Journal of medicinal …, 2014 - liebertpub.com
Citric acid is a weak organic acid found in the greatest amounts in citrus fruits. This study
examined the effect of citric acid on endotoxin-induced oxidative stress of the brain and liver …

Consequences of dynamic high-pressure homogenization pretreatment on the physicochemical and functional characteristics of citric acid-treated whey protein isolate

R Shi, T Li, M Li, G Munkh-Amgalan, A Qayum… - Lwt, 2021 - Elsevier
This study investigated the physicochemical and functional characteristics of citric acid (CA)-
treated whey protein isolate (WPI) by dynamic high-pressure homogenization (DHPH) at …

Protein intake, calcium balance and health consequences

J Calvez, N Poupin, C Chesneau, C Lassale… - European journal of …, 2012 - nature.com
High-protein (HP) diets exert a hypercalciuric effect at constant levels of calcium intake, even
though the effect may depend on the nature of the dietary protein. Lower urinary pH is also …

Metabolic regulation of citrate and iron by aconitases: role of iron–sulfur cluster biogenesis

WH Tong, TA Rouault - Biometals, 2007 - Springer
Iron and citrate are essential for the metabolism of most organisms, and regulation of iron
and citrate biology at both the cellular and systemic levels is critical for normal physiology …

Age and sex effects on plasma metabolite association networks in healthy subjects

A Vignoli, L Tenori, C Luchinat… - Journal of proteome …, 2018 - ACS Publications
In the era of precision medicine, the analysis of simple information like sex and age can
increase the potential to better diagnose and treat conditions that occur more frequently in …

[HTML][HTML] Plasma citrate homeostasis: how it is regulated; and its physiological and clinical implications. An important, but neglected, relationship in medicine

LC Costello, RB Franklin - HSOA journal of human endocrinology, 2016 - ncbi.nlm.nih.gov
The homeostatic maintenance of a normal plasma citrate concentration is an important factor
in humans and in animals; and is required for many normal physiological activities …

[HTML][HTML] Frankincense and myrrh suppress inflammation via regulation of the metabolic profiling and the MAPK signaling pathway

S Su, J Duan, T Chen, X Huang, E Shang, L Yu… - Scientific reports, 2015 - nature.com
Frankincense and myrrh are highly effective in treatment of inflammatory diseases, but
lacking of the therapy mechanisms. We undertook this study to evaluate the effects on …