Since 2015, stroke has become the leading cause of death and disability in China, posing a
significant threat to the health of its citizens as a major chronic non-communicable disease …

Plasma total homocysteine (tHcy) and kidney function are both associated with mortality risk,
but the degree to which kidney function modifies the impact of tHcy on mortality remains …

Hyperhomocysteinemia with hypertension can synergistically increase the risk of stroke. The
China stroke primary prevention trial showed that combining 0.8 mg folic acid (FA) with …

Hyperhomocysteinemia (HHcy) is a condition closely associated with cardiovascular and
cerebrovascular diseases. Detecting its risk factors and taking some relevant interventions …

Objective To determine whether the methylenetetrahydrofolate reductase (MTHFR) C677T
gene polymorphism is linked to the risk of ischaemic stroke and circulating homocysteine …

Objective To investigate the link between genetic variants associated with plasma
homocysteine levels and risk of intracranial aneurysm (IA) using two-sample Mendelian …

Introduction Stroke is a significant public health challenge as it is the second most common
cause of death and the third leading cause of disability globally. Additionally, stroke …

Background H-type hypertension has a high prevalence in China. However, the association
of serum homocysteine levels with 1-year stroke recurrence in patients with acute ischemic …

Abstract Background Blood homocysteine (Hcy) level has become a sensitive indicator in
predicting the development of cardiovascular disease. Studies have shown an association …

Background: Chronic total coronary occlusion is among the most complex coronary artery
diseases. Elevated homocysteine is a risk factor for coronary artery diseases. However, few …