Burden, pathology, and costs of malaria in pregnancy: new developments for an old problem

SJ Rogerson, M Desai, A Mayor, E Sicuri… - The Lancet infectious …, 2018 - thelancet.com
Over the past 10 years, knowledge of the burden, economic costs, and consequences of
malaria in pregnancy has improved, and the prevalence of malaria caused by Plasmodium …

[HTML][HTML] Malaria in pregnancy: from placental infection to its abnormal development and damage

CLL Chua, SKM Khoo, JLE Ong… - Frontiers in …, 2021 - frontiersin.org
Malaria remains a global health burden with Plasmodium falciparum accounting for the
highest mortality and morbidity. Malaria in pregnancy can lead to the development of …

[HTML][HTML] Congenital transmission of apicomplexan parasites: a review

M Rojas-Pirela, L Medina, MV Rojas… - Frontiers in …, 2021 - frontiersin.org
Apicomplexans are a group of pathogenic protists that cause various diseases in humans
and animals that cause economic losses worldwide. These unicellular eukaryotes are …

[HTML][HTML] Placental Sequestration of Plasmodium falciparum Malaria Parasites Is Mediated by the Interaction Between VAR2CSA and Chondroitin Sulfate A on …

M Ayres Pereira, T Mandel Clausen, C Pehrson… - PLoS …, 2016 - journals.plos.org
During placental malaria, Plasmodium falciparum infected erythrocytes sequester in the
placenta, causing health problems for both the mother and fetus. The specific adherence is …

Correlates of malaria vaccine efficacy

DI Stanisic, MBB McCall - Expert Review of Vaccines, 2021 - Taylor & Francis
Introduction: An effective vaccine against malaria forms a global health priority. Both
naturally acquired immunity and sterile protection induced by irradiated sporozoite …

[HTML][HTML] Placental structure in preterm birth among HIV-positive versus HIV-negative women in Kenya

MM Obimbo, Y Zhou, MT McMaster… - JAIDS Journal of …, 2019 - journals.lww.com
Background: Preterm birth (PTB) is a major cause of infant morbidity and mortality in
developing countries. Recent data suggest that in addition to Human Immunodeficiency …

[HTML][HTML] Placental models for evaluation of nanocarriers as drug delivery systems for pregnancy associated disorders

L Fliedel, K Alhareth, N Mignet, T Fournier, K Andrieux - Biomedicines, 2022 - mdpi.com
Pregnancy-associated disorders affect around 20% of pregnancies each year around the
world. The risk associated with pregnancy therapeutic management categorizes pregnant …

A review of ex vivo placental perfusion models: an underutilized but promising method to study maternal-fetal interactions

P Calis, L Vojtech, F Hladik… - The Journal of Maternal …, 2022 - Taylor & Francis
Studying the placenta can provide information about the mechanistic pathways of pregnancy
disease. However, analyzing placental tissues and manipulating placental function in real …

[HTML][HTML] Clinical development of placental malaria vaccines and immunoassays harmonization: a workshop report

A Chêne, S Houard, MA Nielsen, S Hundt, F D'Alessio… - 2016 - Springer
Placental malaria caused by Plasmodium falciparum infection constitutes a major health
problem manifesting as severe disease and anaemia in the mother, impaired fetal …

Pre-clinical and clinical development of the first placental malaria vaccine

C Pehrson, A Salanti, TG Theander… - Expert Review of …, 2017 - Taylor & Francis
Introduction: Malaria during pregnancy is a massive health problem in endemic areas.
Placental malaria infections caused by Plasmodium falciparum are responsible for up to one …