Exposure to metal mixtures in association with cardiovascular risk factors and outcomes: a scoping review
Since the National Institute of Environmental Health Sciences (NIEHS) declared conducting
combined exposure research as a priority area, literature on chemical mixtures has grown …
combined exposure research as a priority area, literature on chemical mixtures has grown …
Integrating multiscale geospatial environmental data into large population health studies: challenges and opportunities
Quantifying the exposome is key to understanding how the environment impacts human
health and disease. However, accurately, and cost-effectively quantifying exposure in large …
health and disease. However, accurately, and cost-effectively quantifying exposure in large …
Machine learning assisted discovery of interactions between pesticides, phthalates, phenols, and trace elements in child neurodevelopment
A growing body of literature suggests that developmental exposure to individual or mixtures
of environmental chemicals (ECs) is associated with autism spectrum disorder (ASD) …
of environmental chemicals (ECs) is associated with autism spectrum disorder (ASD) …
AI/ML-driven advances in untargeted metabolomics and exposomics for biomedical applications
LM Petrick, N Shomron - Cell Reports Physical Science, 2022 - cell.com
Metabolomics describes a high-throughput approach for measuring a repertoire of
metabolites and small molecules in biological samples. One utility of untargeted …
metabolites and small molecules in biological samples. One utility of untargeted …
Prenatal lead exposure is associated with reduced abundance of beneficial gut microbial cliques in late childhood: an investigation using microbial co-occurrence …
Many analytical methods used in gut microbiome research focus on either single bacterial
taxa or the whole microbiome, ignoring multibacteria relationships (microbial cliques). We …
taxa or the whole microbiome, ignoring multibacteria relationships (microbial cliques). We …
Associations of exposure to metal and metal mixtures with thyroid hormones: results from the NHANES 2007–2012
Background Disrupted thyroid homeostasis plays a role in neurocognitive dysfunction and
metabolic disorders. Since individuals are exposed to multiple metals simultaneously, it is …
metabolic disorders. Since individuals are exposed to multiple metals simultaneously, it is …
Evaluating chemical mixtures in epidemiological studies to inform regulatory decisions
DA Savitz, AM Hattersley - Environmental health perspectives, 2023 - ehp.niehs.nih.gov
Background: Epidemiological studies are increasingly going beyond the evaluation of health
effects of individual chemicals to consider chemical mixtures. To our knowledge, the …
effects of individual chemicals to consider chemical mixtures. To our knowledge, the …
Association of postnatal exposure to mixture of bisphenol A, Di-n-butyl phthalate and Di-(2-ethylhexyl) phthalate with Children's IQ at 5 Years of age: Mothers and …
Early childhood is important for neurodevelopment, and exposure to endocrine disruptors
such as bisphenol A (BPA) and phthalates in this period may cause neurodevelopmental …
such as bisphenol A (BPA) and phthalates in this period may cause neurodevelopmental …
A novel approach for the prediction and analysis of daily concentrations of particulate matter using machine learning
Traditional air quality analysis and prediction methods depend on the statistical and
numerical analyses of historical air quality data with more information related to a specific …
numerical analyses of historical air quality data with more information related to a specific …
Estimating effects of longitudinal and cumulative exposure to PFAS mixtures on early adolescent body composition
JR Kuiper, SH Liu, BP Lanphear… - American journal of …, 2024 - academic.oup.com
Few methods have been used to characterize repeatedly measured biomarkers of chemical
mixtures. We applied latent profile analysis (LPA) to serum concentrations of 4 perfluoroalkyl …
mixtures. We applied latent profile analysis (LPA) to serum concentrations of 4 perfluoroalkyl …