Exposure to metal mixtures in association with cardiovascular risk factors and outcomes: a scoping review

G Yim, Y Wang, CG Howe, ME Romano - Toxics, 2022 - mdpi.com
Since the National Institute of Environmental Health Sciences (NIEHS) declared conducting
combined exposure research as a priority area, literature on chemical mixtures has grown …

Integrating multiscale geospatial environmental data into large population health studies: challenges and opportunities

Y Cui, KM Eccles, RK Kwok, BR Joubert, KP Messier… - Toxics, 2022 - mdpi.com
Quantifying the exposome is key to understanding how the environment impacts human
health and disease. However, accurately, and cost-effectively quantifying exposure in large …

Machine learning assisted discovery of interactions between pesticides, phthalates, phenols, and trace elements in child neurodevelopment

V Midya, CS Alcala, E Rechtman… - Environmental …, 2023 - ACS Publications
A growing body of literature suggests that developmental exposure to individual or mixtures
of environmental chemicals (ECs) is associated with autism spectrum disorder (ASD) …

AI/ML-driven advances in untargeted metabolomics and exposomics for biomedical applications

LM Petrick, N Shomron - Cell Reports Physical Science, 2022 - cell.com
Metabolomics describes a high-throughput approach for measuring a repertoire of
metabolites and small molecules in biological samples. One utility of untargeted …

Prenatal lead exposure is associated with reduced abundance of beneficial gut microbial cliques in late childhood: an investigation using microbial co-occurrence …

V Midya, JM Lane, C Gennings… - … science & technology, 2023 - ACS Publications
Many analytical methods used in gut microbiome research focus on either single bacterial
taxa or the whole microbiome, ignoring multibacteria relationships (microbial cliques). We …

Associations of exposure to metal and metal mixtures with thyroid hormones: results from the NHANES 2007–2012

K Kim, M Argos, VW Persky, S Freels, RM Sargis… - Environmental …, 2022 - Elsevier
Background Disrupted thyroid homeostasis plays a role in neurocognitive dysfunction and
metabolic disorders. Since individuals are exposed to multiple metals simultaneously, it is …

Evaluating chemical mixtures in epidemiological studies to inform regulatory decisions

DA Savitz, AM Hattersley - Environmental health perspectives, 2023 - ehp.niehs.nih.gov
Background: Epidemiological studies are increasingly going beyond the evaluation of health
effects of individual chemicals to consider chemical mixtures. To our knowledge, the …

Association of postnatal exposure to mixture of bisphenol A, Di-n-butyl phthalate and Di-(2-ethylhexyl) phthalate with Children's IQ at 5 Years of age: Mothers and …

D Ham, M Ha, H Park, YC Hong, Y Kim, E Ha, S Bae - Chemosphere, 2024 - Elsevier
Early childhood is important for neurodevelopment, and exposure to endocrine disruptors
such as bisphenol A (BPA) and phthalates in this period may cause neurodevelopmental …

A novel approach for the prediction and analysis of daily concentrations of particulate matter using machine learning

B Panneerselvam, N Ravichandran, UC Dumka… - Science of the Total …, 2023 - Elsevier
Traditional air quality analysis and prediction methods depend on the statistical and
numerical analyses of historical air quality data with more information related to a specific …

Estimating effects of longitudinal and cumulative exposure to PFAS mixtures on early adolescent body composition

JR Kuiper, SH Liu, BP Lanphear… - American journal of …, 2024 - academic.oup.com
Few methods have been used to characterize repeatedly measured biomarkers of chemical
mixtures. We applied latent profile analysis (LPA) to serum concentrations of 4 perfluoroalkyl …