Stroke is a devastating condition with significant morbidity and mortality worldwide.
Antithrombotic therapy plays a crucial role in both primary and secondary prevention of …

Aim. Though combination of clopidogrel added to aspirin has been compared to aspirin
alone in patients with stroke or transient ischemic attack, limited data exists on the relative …

Acute ischemic stroke (AIS) is the most common type of stroke and requires immediate
reperfusion. Current acute reperfusion therapies comprise the administration of intravenous …

Objective To evaluate the risks of recurrent stroke and major bleeding events with
clopidogrel and aspirin use among patients aged 80 years or older. Patients and Methods …

Background Patients with ischemic stroke are often treated with clopidogrel monotherapy as
part of secondary stroke prevention. The prevalence of loss of function (LOF) mutations in …

Purpose In light of recently published guidelines from the US Food and Drug Administration
(FDA) on the communication of real-world data (RWD) and real-world evidence (RWE) to …

Introduction Stroke is a leading cause of death and disability worldwide. Antiplatelet
therapies are recommended to reduce the risk of recurrent stroke in patients with ischemic …

Background There is no clear consensus on whether aspirin offers better outcomes in terms
of secondary cardiovascular disease prevention compared with clopidogrel. Objective The …

Purpose Dual antiplatelet therapy (DAT) with clopidogrel and aspirin is not suitable for
clopidogrel resistance (CR) patients with aspirin intolerance. To investigate the prevalence …

Omeprazole is commonly co-prescribed with clopidogrel. Clopidogrel requires bio-activation
by cytochrome P450 CYP2C19. Omeprazole may reduce clopidogrel's antithrombotic …