Toxic effects of glyphosate on the nervous system: a systematic review

C Costas-Ferreira, R Durán, LRF Faro - International journal of molecular …, 2022 - mdpi.com
Glyphosate, a non-selective systemic biocide with broad-spectrum activity, is the most widely
used herbicide in the world. It can persist in the environment for days or months, and its …

Oxidative stress in ischemia/reperfusion injuries following acute ischemic stroke

A Jurcau, AI Ardelean - Biomedicines, 2022 - mdpi.com
Recanalization therapy is increasingly used in the treatment of acute ischemic stroke.
However, in about one third of these patients, recanalization is followed by …

[HTML][HTML] ncRNA-mediated ceRNA regulatory network: Transcriptomic insights into breast cancer progression and treatment strategies

S Yang, X Wang, X Zhou, L Hou, J Wu, W Zhang… - Biomedicine & …, 2023 - Elsevier
With the rapid development of next-generation sequencing technology, several studies have
shown that ncRNAs can act as competitive endogenous RNAs (ceRNAs) and are involved in …

[HTML][HTML] Molecular pathophysiological mechanisms of ischemia/reperfusion injuries after recanalization therapy for acute ischemic stroke

A Jurcau, IA Ardelean - Journal of integrative neuroscience, 2021 - imrpress.com
With the larger variety of methods employed, recanalization therapy is increasingly used to
treat acute ischemic stroke resulting in about one-third of patients undergoing early …

Therapeutic strategies targeting mitochondrial calcium signaling: a new hope for neurological diseases?

LR Rodríguez, T Lapeña-Luzón, N Benetó… - Antioxidants, 2022 - mdpi.com
Calcium (Ca2+) is a versatile secondary messenger involved in the regulation of a plethora
of different signaling pathways for cell maintenance. Specifically, intracellular Ca2+ …

Calcium dyshomeostasis drives pathophysiology and neuronal demise in age-related neurodegenerative diseases

G Griffioen - International journal of molecular sciences, 2023 - mdpi.com
This review postulates that age-related neurodegeneration entails inappropriate activation
of intrinsic pathways to enable brain plasticity through deregulated calcium (Ca2+) …

Molecular mechanism of cognitive impairment associated with Parkinson's disease: A stroke perspective

S Gupta, J Khan, S Ghosh - Life Sciences, 2023 - Elsevier
Parkinson's disease (PD) is a common neurological illness that causes several motor and
non-motor symptoms, most characteristically limb tremors and bradykinesia. PD is a slowly …

Role of Ca2+/Calmodulin-Dependent Protein Kinase Type II in Mediating Function and Dysfunction at Glutamatergic Synapses

AG Mohanan, S Gunasekaran, RS Jacob… - Frontiers in molecular …, 2022 - frontiersin.org
Glutamatergic synapses harbor abundant amounts of the multifunctional Ca2+/calmodulin-
dependent protein kinase type II (CaMKII). Both in the postsynaptic density as well as in the …

Advancement of epigenetics in stroke

J Peng, D Ghosh, F Zhang, L Yang, J Wu… - Frontiers in …, 2022 - frontiersin.org
A wide plethora of intervention procedures, tissue plasminogen activators, mechanical
thrombectomy, and several neuroprotective drugs were reported in stroke research over the …

Disturbance of glutamate metabolism and inhibition of CaM-CaMKII-CREB signaling pathway in the hippocampus of mice induced by 1, 2-dichloroethane exposure

W Huang, Z Wang, G Wang, K Li, Y Jin, F Zhao - Environmental Pollution, 2022 - Elsevier
Dichloroethane (1, 2-DCE) is a highly toxic neurotoxicity, and the brain tissue is the main
target organ. At present, long-term exposure to 1, 2-DCE has been shown to cause cognitive …