Molecular genetics and complex inheritance of congenital heart disease

NS Diab, S Barish, W Dong, S Zhao, G Allington, X Yu… - Genes, 2021 - mdpi.com
Congenital heart disease (CHD) is the most common congenital malformation and the
leading cause of mortality therein. Genetic etiologies contribute to an estimated 90% of CHD …

Mechanisms of heart valve development and disease

A O'Donnell, KE Yutzey - Development, 2020 - journals.biologists.com
The valves of the heart are crucial for ensuring that blood flows in one direction from the
heart, through the lungs and back to the rest of the body. Heart valve development is …

Harnessing nanotechnology for cardiovascular disease applications-a comprehensive review based on bibliometric analysis

Z Zheng, S Zhu, M Lv, Z Gu, H Hu - Nano Today, 2022 - Elsevier
Cardiovascular diseases (CVDs) remain the leading cause of health problems worldwide.
Nanotechnology, based on its unique properties, provides novel solutions to the diagnosis …

Long-term coronary artery disease risk prediction with machine learning models

M Trigka, E Dritsas - Sensors, 2023 - mdpi.com
The heart is the most vital organ of the human body; thus, its improper functioning has a
significant impact on human life. Coronary artery disease (CAD) is a disease of the coronary …

[PDF][PDF] Multi-omics profiling visualizes dynamics of cardiac development and functions

Y Gu, Y Zhou, S Ju, X Liu, Z Zhang, J Guo, J Gao… - Cell Reports, 2022 - cell.com
Cardiogenesis is a tightly regulated dynamic process through a continuum of differentiation
and proliferation events. Key factors and pathways governing this process remain …

[PDF][PDF] BMP10 signaling promotes the development of endocardial cells from human pluripotent stem cell-derived cardiovascular progenitors

AA Mikryukov, A Mazine, B Wei, D Yang, Y Miao, M Gu… - Cell Stem Cell, 2021 - cell.com
The embryonic endocardium is essential for early heart development as it functions to
induce trabecular myocardium, the first heart tissue to form, and is the source of the cells that …

METTL3 achieves lipopolysaccharide-induced myocardial injury via m6A-dependent stabilization of Myh3 mRNA

C Gong, J Wu, H Li, C Luo, G Ji, X Guan, J Liu… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Septic cardiomyopathy (SCM) was an important pathological component of severe sepsis
and septic shock. N6-methyladenosine (m 6 A) modification was a common RNA …

Placental inflammation leads to abnormal embryonic heart development

EJ Ward, S Bert, S Fanti, KM Malone, RT Maughan… - Circulation, 2023 - Am Heart Assoc
Background: Placental heart development and embryonic heart development occur in
parallel, and these organs have been proposed to exert reciprocal regulation during …

Automatic classification and diagnosis of heart valve diseases using heart sounds with MFCC and proposed deep model

M Yildirim - Concurrency and Computation: Practice and …, 2022 - Wiley Online Library
Heart sounds have been widely used for years to monitor and classify heart diseases.
Experts manually examine these sounds, which is arduous and time‐consuming. In addition …

Soft electronics for advanced infant monitoring

M Yuan, Y Long, T Liu, J Liu, S Qiu, T Lin, F Xu, Y Fang - Materials Today, 2024 - Elsevier
Infants are exceptionally fragile and physically vulnerable who need special healthcare.
Continuous monitoring of vital information of infants is essential for understanding their …