Systemic therapy for melanoma brain and leptomeningeal metastases
WJ Sherman, E Romiti, L Michaelides… - … treatment options in …, 2023 - Springer
Opinion statement Melanoma has a high propensity to metastasize to the brain which
portends a poorer prognosis. With advanced radiation techniques and targeted therapies …
portends a poorer prognosis. With advanced radiation techniques and targeted therapies …
Immunotherapy revolutionizing brain metastatic cancer treatment: personalized strategies for transformative outcomes
T Li, S Sun, Y Li, Y Zhang, L Wei - Frontiers in Immunology, 2024 - frontiersin.org
Brain metastatic cancer poses a significant clinical challenge, with limited treatment options
and poor prognosis for patients. In recent years, immunotherapy has emerged as a …
and poor prognosis for patients. In recent years, immunotherapy has emerged as a …
Detection of cell‐free tumor DNA in cerebrospinal fluid as a diagnostic biomarker for leptomeningeal melanoma metastasis: A case series
I Dirven, M Vounckx, JI Kessels… - Pigment Cell & …, 2024 - Wiley Online Library
Leptomeningeal melanoma metastases (LMM) are associated with poor survival. Diagnosis
is based on clinical presentation, brain MRI and cerebrospinal fluid (CSF) analysis …
is based on clinical presentation, brain MRI and cerebrospinal fluid (CSF) analysis …
Malignant melanoma meningeal metastasis with concurrent hemorrhagic cerebrospinal fluid: A case report
Q Ma, B Song, K Cao, X She, W Chen… - Oncology …, 2024 - spandidos-publications.com
Malignant melanoma meningeal metastasis (MMMM) is a rare clinical condition with a poor
prognosis. The observation of hemorrhagic cerebrospinal fluid (CSF) in this type of disease …
prognosis. The observation of hemorrhagic cerebrospinal fluid (CSF) in this type of disease …
HMGA2 对软脑膜转移黑色素瘤细胞迁移和增殖的影响
李晓辉， 赵加旭， 彭海豹， 张叶， 曾睿， 迟喻丹 - 中国癌症杂志, 2024 - china-oncology.com
背景与目的: 软脑膜转移是黑色素瘤中枢神经系统转移的一种形式, 高迁移率族蛋白A2 (high-
mobility group protein A2, HMGA2) 已被证实在多种肿瘤的发生, 发展过程中起重要作用 …
mobility group protein A2, HMGA2) 已被证实在多种肿瘤的发生, 发展过程中起重要作用 …
Risk factors associated with leptomeningeal metastases after postoperative stereotactic radiotherapy for brain metastases
JA Crouzen, AL Petoukhova, M Hakstege… - 2024 - researchsquare.com
Methods: We included 147 patients who underwent resection and SRT for BMs. Univariable
and multivariable Cox regression analyses were used to assess associations of LMD with …
and multivariable Cox regression analyses were used to assess associations of LMD with …
Effects of HMGA2 on migration and proliferation of leptomeningeal metastatic melanoma
LI Xiaohui, Z Jiaxu, P Haibao, Z Ye, Z Rui… - China …, 2024 - china-oncology.com
Background and purpose: Leptomeningeal metastasis is a form of central nervous system
metastasis of melanoma. High mobility group A2 (HMGA2) has been proven to play an …
metastasis of melanoma. High mobility group A2 (HMGA2) has been proven to play an …