encompassed by follicular cells but not on follicular cell monolayer, unless removal of the
zona allows coupling (Buccione et al., 1987). FSH or estradiol does not seem beneficial …

The role of calcium in the regulation of both the meiotic and mitotic cell cycles has been the
subject of considerable investigation in the nonmammalian field. In contrast, the …

The efficacy of follicle‐stimulating hormone (FSH), epidermal growth factor (EGF), and
dibutyryl cGMP (dbcGMP) as inducers of germinal vesicle breakdown (GVBD) in cumulus …

Abstract Bovine follicular oocytes (N= 5991) were exposed to an analog of cyclic adenosine
3′, 5′-monophosphate (cAMP), dibutyryl cyclic AMP (db-cAMP)(2.5, 5, and 10 mM), the …

Ribonucleic acid synthesis continues at a low rate within 1 h of germinal vesicle breakdown.
To determine if this newly synthesized mRNA is required for the resumption of meiosis in …

The second messenger cyclic adenosine 5′ monophosphate (cAMP) has been implicated
in controlling meiotic maturation. To date, there have been no direct measurements of cAMP …

Experiments were performed to determine if elevation of cumulus cell cAMP results in an
increase in mouse oocyte cAMP while the heterologous gap junctions were intact. Both …

Cyclic adenosine monophosphate (cAMP) has been implicated as an important regulator of
meiotic maturation in mammalian oocytes. A decrease in cAMP, brought about by the action …

We have studied the effect of agents known to stimulate adenylate cyclase on spontaneous
meiotic resumption in vitro by mouse oocytes. We have found that cholera toxin (CT)(up to 1 …

This study addresses the role of cAMP hydrolytic isoenzyme phosphodiesterase type 3 (PDE
3) modulation on human oocyte maturation in vitro. Presence of phosphodiesterase type 3 A …