Pre-existing cross-reactive immune responses to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) proteins in infection-naive subjects have been described by …

Over the past year, numerous studies in the peer reviewed and preprint literature have
reported on the virological, epidemiological and clinical characteristics of the coronavirus …

With the high rate of COVID-19 infections worldwide, the emergence of SARS-CoV-2
variants was inevitable. Several mutations have been identified in the SARS-CoV-2 …

The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …

Background Studies of T-cell immune responses against SARS-CoV-2 are important in
understanding the immune status of individuals or populations. Here, we use a simple …

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which causes
coronavirus-19 (COVID-19), has caused significant morbidity and mortality globally. In …

Cell-mediated immunity is critical for long-term protection against most viral infections,
including coronaviruses. We studied 23 severe acute respiratory syndrome coronavirus 2 …

SARS-CoV-2 variants and seasonal coronaviruses continue to cause disease and
coronaviruses in the animal reservoir pose a constant spillover threat. Importantly …

Targeted synthetic vaccines have the potential to transform our response to viral outbreaks,
yet the design of these vaccines requires a comprehensive knowledge of viral immunogens …

Objectives Potential differences in the breadth, distribution and magnitude of CD4+ T‐cell
responses directed against the SARS‐CoV‐2 spike glycoprotein between vaccinees, COVID …