Pancreatic endocrine tumors (PETs) have long fascinated clini-cians, because some can
release biologically active hormones that cause distinct syndromes and provide important …

Learning Objectives Assess the basic aspects of PNET tumor biology, pathogenesis, and
classification. Explain the epidemiology and evaluate the prognosis of PNET patients …

In patients with multiple endocrine neoplasia type 1 (MEN1), the most common functional
pancreatic endocrine tumor (PET) syndrome is Zollinger-Ellison syndrome (ZES). ZES has …

Pancreatic endocrine tumors have been steadily growing in incidence and prevalence
during the last two decades, showing an incidence of 4–5/1,000,000 population. They …

This review focuses on discussing the main modifications of the recently published 2017
WHO Classification of Neoplasms of the Neuroendocrine Pancreas (panNEN). Recent …

The WHO classifies nonfunctioning pancreatic NETs according to the uniform classification
scheme for endocrine tumors, independent of the site of the primary:(1) well-differentiated …

Objective: To analyze the penetrance and clinical course of isolated nonfunctioning tumors
of the pancreas (NFTP) in MEN 1 patients, and to propose a strategy for managing them …

Objective: Highlight unresolved controversies in the management of Zollinger-Ellison
syndrome (ZES). Summary Background Data: Recent studies have resolved some of the …

Neuroendocrine tumours of the gastrointestinal tract and pancreas present a major
challenge to physicians in their recognition and treatment requirements, and surgical …

Background The management of small, nonfunctioning pancreaticoduodenal endocrine
tumors (NFPET) in multiple endocrine neoplasia type 1 (MEN1) patients is still controversial …