The nature of immune responses to urinary tract infections

SN Abraham, Y Miao - Nature Reviews Immunology, 2015 - nature.com
The urinary tract is constantly exposed to microorganisms that inhabit the gastrointestinal
tract, but generally the urinary tract resists infection by gut microorganisms. This resistance …

[HTML][HTML] Host–pathogen interactions in urinary tract infection

GR Nielubowicz, HLT Mobley - Nature Reviews Urology, 2010 - nature.com
The urinary tract is a common site of bacterial infections; nearly half of all women experience
at least one urinary tract infection (UTI) during their lifetime. These infections are classified …

Urinary tract infection: self-reported incidence and associated costs

B Foxman, R Barlow, H D'Arcy, B Gillespie… - Annals of …, 2000 - Elsevier
PURPOSE: To estimate the annual incidence, cumulative probability of presumed urinary
tract infection (UTI) by age, and the social costs. METHODS: Analysis of a random digit …

Type 1 fimbrial expression enhances Escherichia coli virulence for the urinary tract.

I Connell, W Agace, P Klemm… - Proceedings of the …, 1996 - National Acad Sciences
Type 1 fimbriae are adhesion organelles expressed by many Gram-negative bacteria. They
facilitate adherence to mucosal surfaces and inflammatory cells in vitro, but their contribution …

Role of biofilm in catheter-associated urinary tract infection

BW Trautner, RO Darouiche - American journal of infection control, 2004 - Elsevier
The predominant form of life for the majority of microorganisms in any hydrated biologic
system is a cooperative community termed a “biofilm.” A biofilm on an indwelling urinary …

Bad bugs and beleaguered bladders: Interplay between uropathogenic Escherichia coli and innate host defenses

MA Mulvey, JD Schilling, JJ Martinez… - Proceedings of the …, 2000 - National Acad Sciences
Strains of uropathogenic Escherichia coli (UPEC) are the causative agents in the vast
majority of all urinary tract infections. Upon entering the urinary tract, UPEC strains face a …

[HTML][HTML] Urinary tract infections caused by Pseudomonas aeruginosa: a minireview

R Mittal, S Aggarwal, S Sharma, S Chhibber… - Journal of infection and …, 2009 - Elsevier
Urinary tract infections (UTIs) are a serious health problem affecting millions of people each
year. Infections of the urinary tract are the second most common type of infection in the body …

Dynamic persistence of UPEC intracellular bacterial communities in a human bladder-chip model of urinary tract infection

K Sharma, N Dhar, VV Thacker, TM Simonet… - Elife, 2021 - elifesciences.org
Uropathogenic Escherichia coli (UPEC) proliferate within superficial bladder umbrella cells
to form intracellular bacterial communities (IBCs) during early stages of urinary tract …

Secretion of proinflammatory cytokines by epithelial cells in response to Chlamydia infection suggests a central role for epithelial cells in chlamydial pathogenesis.

SJ Rasmussen, L Eckmann, AJ Quayle… - The Journal of …, 1997 - Am Soc Clin Investig
Chlamydia species infect epithelial cells at mucosal surfaces, and are major causes of
sexually transmitted diseases. Infection is characterized by inflammation which is …

Local Chemokine Paralysis, a Novel Pathogenic Mechanism for Porphyromonas gingivalis

RP Darveau, CM Belton, RA Reife… - Infection and …, 1998 - Am Soc Microbiol
Periodontitis, which is widespread in the adult population, is a persistent bacterial infection
associated with Porphyromonas gingivalis. Gingival epithelial cells are among the first cells …