Periodontitis, which is widespread in the adult population, is a persistent bacterial infection
associated with Porphyromonas gingivalis. Gingival epithelial cells are among the first cells …

Innovative solutions are needed for the treatment of bacterial infections, and a range of
antibacterial molecules have been explored as alternatives to antibiotics. A different …

Urinary tract infection (UTI) caused by uropathogenic Escherichia coli (UPEC) is a
substantial economic and societal burden—a formidable public health issue. Symptomatic …

Respiratory epithelial cells play a crucial role in the inflammatory response during
Pseudomonas aeruginosa infection in the lungs of patients with cystic fibrosis. In this study …

AIMS--To use a range of natural phenotypically variant strains of Helicobacter pylori with
disparate CagA and VacA (vacuolating cytotoxin) expression to determine which bacterial …

Bacteriuria is associated with acute disease conditions of varying severity. 48, 62
Consequently, the definition of bacterial virulence for the urinary tract depends on the end …

The expression of adhesion molecules and the local production of chemotactic cytokines
within the epithelium are considered to be key events in neutrophil (PMN) migration at sites …

Mucosal pathogens trigger a local innate host response by activating epithelial cells.
Bacterial adherence and Toll-like receptor 4 (TLR4) signaling have been implicated as key …

AIMS--To investigate:(1) whether Helicobacter pylori directly induces interleukin-8 (IL-8)
message expression and protein secretion in established gastric epithelial cell lines; and (2) …

The prompt recruitment of neutrophils to the site of infection is essential for the defense of
the bovine mammary gland against invading pathogens and is determinant for the outcome …