Intestinal epithelial cells as watchdogs for the natural immune system

L Eckmann, MF Kagnoff, J Fierer - Trends in Microbiology, 1995 - cell.com
Intestinal epithelial cells secrete a spectrum of chemoattractant and proinflammatory
cytokines after invasion by bacteria. We suggest the novel concept that epithelial cells not …

Molecular factors associated with compartmentalization of gingival immune responses and transepithelial neutrophil migration

MS Tonetti - Journal of periodontal research, 1997 - Wiley Online Library
PMN migration into the gingival sulcus is a tightly regulated process aimed at selectively
increasing leukocyte availability at the site of bacterial plaque aggression, ie the superficial …

Urinary interleukin-6 and interleukin-8 in children with urinary tract infection

BA Jantausch, R O'Donnell, BL Wiedermann - Pediatric Nephrology, 2000 - Springer
Abstract Urinary interleukin-6 (UIL-6) and urinary interleukin-8 (UIL-8) concentrations were
measured by immunoassay in 39 and 34 patients respectively, hospitalized with febrile …

Comparison of asymptomatic bacteriuria Escherichia coli isolates from healthy individuals versus those from hospital patients shows that long-term bladder …

E Salvador, F Wagenlehner, CD Köhler… - Infection and …, 2012 - Am Soc Microbiol
Asymptomatic bacteriuria (ABU) is a condition where bacteria stably colonize the urinary
tract, in a manner closely resembling commensalism at other mucosal sites. The patients …

[HTML][HTML] Molecular basis of acute cystitis reveals susceptibility genes and immunotherapeutic targets

I Ambite, M Puthia, K Nagy, C Cafaro, A Nadeem… - PLoS …, 2016 - journals.plos.org
Tissue damage is usually regarded as a necessary price to pay for successful elimination of
pathogens by the innate immune defense. Yet, it is possible to distinguish protective from …

CXCR2 knockout mice are protected against DSS-colitis-induced acute kidney injury and inflammation

P Ranganathan, C Jayakumar… - American Journal …, 2013 - journals.physiology.org
Organ cross talk exists in many diseases of the human and animal models of human
diseases. A recent study demonstrated that inflammatory mediators can cause acute kidney …

Urinary tract infection of mice to model human disease: practicalities, implications and limitations

AJ Carey, CK Tan, DS Ipe, MJ Sullivan… - Critical reviews in …, 2016 - Taylor & Francis
Urinary tract infections (UTIs) are among the most common bacterial infections in humans.
Murine models of human UTI are vital experimental tools that have helped to elucidate UTI …

[HTML][HTML] A Metaproteomics Approach to Elucidate Host and Pathogen Protein Expression during Catheter-Associated Urinary Tract Infections (CAUTIs)[S]

C Lassek, M Burghartz, D Chaves-Moreno… - Molecular & Cellular …, 2015 - ASBMB
Long-term catheterization inevitably leads to a catheter-associated bacteriuria caused by
multispecies bacterial biofilms growing on and in the catheters. The overall goal of the …

The roles of the host and the pathogens in urinary tract infections

B Köves, B Wullt - European Urology Supplements, 2016 - Elsevier
The severity of urinary tract infections (UTIs) varies depending on the balance between the
virulence of the infecting bacterial strain and the antibacterial host defense. Bacterial …

Uroepithelial cells are part of a mucosal cytokine network

S Hedges, W Agace, M Svensson… - Infection and …, 1994 - Am Soc Microbiol
This study compared the cytokine production of uroepithelial cell lines in response to gram-
negative bacteria and inflammatory cytokines. Human kidney (A498) and bladder (J82) …