[HTML][HTML] Role of the NLRP3 inflammasome in autoimmune diseases

Z Li, J Guo, L Bi - Biomedicine & pharmacotherapy, 2020 - Elsevier
NOD-like receptor family pyrin domain containing 3 (NLRP3) is an intracellular receptor that
senses foreign pathogens and endogenous danger signals. It assembles with apoptosis …

Curcumin: an inflammasome silencer

S Hasanzadeh, MI Read, AR Bland, M Majeed… - Pharmacological …, 2020 - Elsevier
Curcumin is the major bioactive polyphenolic ingredient of turmeric. Increasing evidence
indicates that the health benefits of curcumin are mediated through its anti-inflammatory and …

Experimental and clinical reports on anti‐inflammatory, antioxidant, and immunomodulatory effects of Curcuma longa and curcumin, an updated and comprehensive …

A Memarzia, MR Khazdair, S Behrouz… - …, 2021 - Wiley Online Library
Curcuma longa (C. longa) or turmeric is a plant with a long history of use in traditional
medicine, especially for treating inflammatory conditions C. longa and its main constituent …

NLRP3 inflammasome: checkpoint connecting innate and adaptive immunity in autoimmune diseases

Y Zhang, W Yang, W Li, Y Zhao - Frontiers in immunology, 2021 - frontiersin.org
Autoimmune diseases are a broad spectrum of human diseases that are characterized by
the breakdown of immune tolerance and the production of autoantibodies. Recently …

Curcumin attenuates MSU crystal-induced inflammation by inhibiting the degradation of IκBα and blocking mitochondrial damage

B Chen, H Li, G Ou, L Ren, X Yang, M Zeng - Arthritis research & therapy, 2019 - Springer
Background Gouty arthritis is characterized by the deposition of monosodium urate (MSU)
within synovial joints and tissues due to increased urate concentrations. In this study, we …

NOD-like receptors in autoimmune diseases

L Chen, S Cao, Z Lin, S He, J Zuo - Acta Pharmacologica Sinica, 2021 - nature.com
Autoimmune diseases are chronic immune diseases characterized by dysregulation of
immune system, which ultimately results in a disruption in self-antigen tolerance. Cumulative …

Dietary Curcumin Alleviated Acute Ileum Damage of Ducks (Anas platyrhynchos) Induced by AFB1 through Regulating Nrf2-ARE and NF-κB Signaling Pathways

S Jin, H Yang, Y Jiao, Q Pang, Y Wang, M Wang… - Foods, 2021 - mdpi.com
Aflatoxin B1 (AFB1) is a stable toxic metabolite threatening health of human and animal and
widely contaminated animal feed and human food. This present study aimed to investigate …

Immunomodulatory effects of diet and nutrients in systemic lupus erythematosus (SLE): a systematic review

MA Islam, SS Khandker, PJ Kotyla… - Frontiers in …, 2020 - frontiersin.org
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multiple
organ involvement, including the skin, joints, kidneys, lungs, central nervous system and the …

Inflammasomes in common immune-related skin diseases

L Tang, F Zhou - Frontiers in immunology, 2020 - frontiersin.org
The inflammasome is an important protein complex that cleaves the proinflammatory
cytokines pro-IL-1β and pro-IL-18 into their active forms. Owing to its critical role in eliciting …

COVID‐19: A case for inhibiting NLRP3 inflammasome, suppression of inflammation with Curcumin?

A Saeedi‐Boroujeni… - Basic & Clinical …, 2021 - Wiley Online Library
Curcumin is the effective ingredient of turmeric, sometimes used as a painkiller in traditional
medicine. It has extensive biological properties such as anti‐inflammatory and antioxidant …