Cell adhesion molecules in chemically-induced renal injury

WC Prozialeck, JR Edwards - Pharmacology & therapeutics, 2007 - Elsevier
Cell adhesion molecules are integral cell–membrane proteins that maintain cell–cell and
cell–substrate adhesion and in some cases act as regulators of intracellular signaling …

Non-genotoxic carcinogens: early effects on gap junctions, cell proliferation and apoptosis in the rat

A Mally, JK Chipman - Toxicology, 2002 - Elsevier
Non-genotoxic carcinogens are thought to induce tumour formation by disturbing the
balance between cell growth and cell death. Gap junctions (GJ) contribute to the …

[HTML][HTML] Connexin43 is associated with the progression of clear cell renal carcinoma and is regulated by tangeretin to sygergize with tyrosine kinase inhibitors

Y Lai, W Wu, X Liang, F Zhong, L An, Z Chang… - Translational …, 2023 - Elsevier
Abstract Background The roles of Connexin43 (Cx43) in clear cell renal cell carcinoma
(ccRCC) microenviroment remains to be poorly defined. Methods The expression profile …

Prevention of renal cell carcinoma by active vitamin D3

T Fujioka, Y Suzuki, T Okamoto, N Mastushita… - World journal of …, 2000 - Springer
A bstract We studied the serum levels of 1, 25-dihydroxyvitamin D [1, 25 (OH) 2 D (Vit D)] in
patients with renal cell carcinoma (RCC) and the influence of 1, 25 (OH) 2 D 3 (Vit D 3) on …

Ochratoxin A alters cell adhesion and gap junction intercellular communication in MDCK cells

A Mally, M Decker, M Bekteshi, W Dekant - Toxicology, 2006 - Elsevier
Ochratoxin A (OTA) is one of the most potent renal carcinogens studied to date, but the
mechanism of tumor formation by ochratoxin A remains largely unknown. Cell adhesion and …

Cytotoxicity of adenoviral-mediated cytosine deaminase plus 5-fluorocytosine gene therapy is superior to thymidine kinase plus acyclovir in a human renal cell …

T SHIRAKAWA, TA GARDNER, SCHU KO… - The journal of …, 1999 - auajournals.org
Abstract Purpose: An estimated 11,600 Americans will die of renal cell carcinoma in 1998.
The lack of effective chemotherapy or radiotherapy requires the investigation of novel …

Antioxidant potential and gap junction-mediated intercellular communication as early biological markers of mercuric chloride toxicity in the MDCK cell line

MF Aleo, F Morandini, F Bettoni, S Tanganelli… - Toxicology in vitro, 2002 - Elsevier
In this study, the early nephrotoxic potential of mercuric chloride (HgCl2) has been
evaluated in vitro, by exposing a renal-derived cell system, the tubular epithelial Madin …

Curcuma longa extracts suppress pathophysiology of experimental hepatic parenchymal cell necrosis

DO Adeyemi, PO Awoniran - Pathophysiology, 2019 - Elsevier
The study sought to investigate the protective potentials of Curcuma longa rhizome following
potassium bromate-induced liver injury in Wistar rats. Thirty-five male Wistar rats were …

The preventive effect of green tea on the gap junction intercellular communication in renal epithelial cells treated with a renal carcinogen

H Takahashi, K Nomata, KI Mori, M Matsuo… - Anticancer …, 2004 - ar.iiarjournals.org
Objective: Clinical studies imply that (-)-epigallocatechin-3-gallate (EGCG), a main
ingredient of green tea catechins, has a chemopreventive action against cancers and …

All-trans retinoic acid enhances gap junctional intercellular communication among renal epithelial cells in vitro treated with renal carcinogens

J Watanabe, K Nomata, M Noguchi, H Satoh… - European Journal of …, 1999 - Elsevier
Epidemiological and clinical studies imply that retinoids have a chemopreventative action
against cancer and can suppress the growth of cancer cells. The regulation of connexin (Cx) …