[HTML][HTML] Platelets in immune response to virus and immunopathology of viral infections

ED Hottz, FA Bozza, PT Bozza - Frontiers in medicine, 2018 - frontiersin.org
Platelets are essential effector cells in hemostasis. Aside from their role in coagulation,
platelets are now recognized as major inflammatory cells with key roles in the innate and …

[HTML][HTML] Dengue virus non-structural protein 1: a pathogenic factor, therapeutic target, and vaccine candidate

HR Chen, YC Lai, TM Yeh - Journal of biomedical science, 2018 - Springer
Dengue virus (DENV) infection is the most common mosquito-transmitted viral infection.
DENV infection can cause mild dengue fever or severe dengue hemorrhagic fever …

[HTML][HTML] Dengue infection-recent advances in disease pathogenesis in the era of COVID-19

YK Yong, WF Wong, R Vignesh… - Frontiers in …, 2022 - frontiersin.org
The dynamics of host-virus interactions, and impairment of the host's immune surveillance
by dengue virus (DENV) serotypes largely remain ambiguous. Several experimental and …

[HTML][HTML] Inflammasome fuels dengue severity

G Shrivastava, PC Valenzuela Leon… - Frontiers in cellular and …, 2020 - frontiersin.org
Dengue is an acute febrile disease triggered by dengue virus. Dengue is the widespread
and rapidly transmitted mosquito-borne viral disease of humans. Diverse symptoms and …

Molecular mechanisms in the pathogenesis of dengue infections

GN Malavige, GS Ogg - Trends in Molecular Medicine, 2024 - cell.com
Dengue is the most rapidly emerging climate-sensitive infection, and morbidity/mortality and
disease incidence are rising markedly, leading to healthcare systems being overwhelmed …

[HTML][HTML] Combination of inflammatory and vascular markers in the febrile phase of dengue is associated with more severe outcomes

NL Vuong, PK Lam, DKY Ming, HTL Duyen… - Elife, 2021 - elifesciences.org
Background: Early identification of severe dengue patients is important regarding patient
management and resource allocation. We investigated the association of 10 biomarkers …

[HTML][HTML] Lassa virus activates myeloid dendritic cells but suppresses their ability to stimulate T cells

J Schaeffer, X Carnec, S Reynard, M Mateo… - PLoS …, 2018 - journals.plos.org
Lassa virus (LASV) is responsible for a viral hemorrhagic fever in humans and the death of
3,000 to 5,000 people every year. The immune response to LASV is poorly understood, but …

Increased serum ferritin and interleukin-18 levels in children with dengue

N Valero, J Mosquera, M Torres, A Duran… - Brazilian journal of …, 2019 - Springer
Activated monocytes/macrophages that produce a cytokine storm play an important role in
the pathogenesis of dengue. Interleukin-18 (IL-18) is a proinflammatory cytokine produced …

IL‐18: The Forgotten Cytokine in Dengue Immunopathogenesis

JD Nanda, TS Ho, RD Satria, MK Jhan… - Journal of …, 2021 - Wiley Online Library
Dengue fever is an infection by the dengue virus (DENV) transmitted by vector mosquitoes. It
causes many infections in tropical and subtropical countries every year, thus posing a …

[HTML][HTML] Liver transcriptomics reveals features of the host response in a mouse model of dengue virus infection

W Zheng, Q Yan, Z Li, X Wang, P Wu, F Liao… - Frontiers in …, 2022 - frontiersin.org
Background Dengue virus (DENV) infection induces various clinical manifestations and
even causes organ injuries, leading to severe dengue haemorrhagic fever and dengue …