A review of population pharmacokinetic analyses of linezolid

E Bandín-Vilar, L García-Quintanilla… - Clinical …, 2022 - Springer
In recent years, many studies on population pharmacokinetics of linezolid have been
conducted. This comprehensive review aimed to summarize population pharmacokinetic …

Hematological toxicities associated with linezolid therapy in adults: key findings and clinical considerations

D Cattaneo, DJE Marriott… - Expert Review of Clinical …, 2023 - Taylor & Francis
Introduction Linezolid can cause serious adverse effects including thrombocytopenia and
anemia. Here, we focus specifically on linezolid-related hematological toxicity in adult …

[HTML][HTML] Clinical recommendations of the Russian Scientific Liver Society and Russian Gastroenterological Association on diagnosis and treatment of liver fibrosis …

VT Ivashkin, MV Maevskaya, MS Zharkova… - Russian Journal of …, 2022 - gastro-j.ru
Aim. Current clinical recommendations are intended to supply gastroenterologists,
physicians and general practitioners with modern methods for the diagnosis and treatment …

Expert consensus statement on therapeutic drug monitoring and individualization of linezolid

B Lin, Y Hu, P Xu, T Xu, C Chen, L He, M Zhou… - Frontiers in Public …, 2022 - frontiersin.org
Linezolid is an oxazolidinone antibacterial drug, and its therapeutic drug monitoring and
individualized treatment have been challenged since its approval. With the in-depth clinical …

Proposal of initial and maintenance dosing regimens with linezolid for renal impairment patients

H Kawasuji, Y Tsuji, C Ogami, K Kimoto, A Ueno… - BMC Pharmacology and …, 2021 - Springer
Background Linezolid is administered as a fixed dose to all patients despite evidence of
overexposure and thrombocytopenia in renal impairment. The aims of this study were to …

Rifampicin reduces plasma concentration of linezolid in patients with infective endocarditis

M Bock, JGC Van Hasselt, F Schwartz… - Journal of …, 2023 - academic.oup.com
Background Linezolid in combination with rifampicin has been used in treatment of infective
endocarditis especially for patients infected with staphylococci. Objectives Because …

Клинические рекомендации Российского общества по изучению печени, Российской гастроэнтерологической ассоциации, Российской ассоциации …

ВТ Ивашкин, МВ Маевская, МС Жаркова… - Российский журнал …, 2022 - gastro-j.ru
Аннотация Цель: в клинических рекомендациях, предназначенных для врачей общей
практики, врачей-терапевтов, врачей-гастроэнтерологов, врачей-кардиологов, врачей …

Linezolid population pharmacokinetics in South African adults with drug-resistant tuberculosis

MT Abdelwahab, S Wasserman… - Antimicrobial agents …, 2021 - Am Soc Microbiol
Linezolid is widely used for drug-resistant tuberculosis (DR-TB) but has a narrow therapeutic
index. To inform dose optimization, we aimed to characterize the population …

Linezolid pharmacokinetics: a systematic review for the best clinical practice

S Heidari, H Khalili - European Journal of Clinical Pharmacology, 2023 - Springer
Objectives To summarize the pharmacokinetics of linezolid to optimize the dosing regimen
in special populations. Methods A literature search was performed in three largest medical …

Population pharmacokinetics and target attainment analysis of linezolid in multidrug‐resistant tuberculosis patients

AK Tietjen, N Kroemer, D Cattaneo… - British Journal of …, 2022 - Wiley Online Library
Aim This study investigates the pharmacokinetic/pharmacodynamic (PK/PD) target
attainment of linezolid in patients infected with multidrug‐resistant (MDR) tuberculosis (TB) …