BACKGROUND Economic analyses of new technologies, such as proton‐beam
radiotherapy (PBT), are a public health priority. To date, no systematic review of the cost …

Use of proton beam therapy has expanded, with the number of proton centres rapidly
increasing not only in the USA but also worldwide. The physical characteristics of the proton …

A paradigm shift from current population based medicine to personalized and participative
medicine is underway. This transition is being supported by the development of clinical …

Purpose Reducing dose to normal tissues is the advantage of protons versus photons. We
aimed to describe a method for translating this reduction into a clinically relevant benefit …

Background We report the first clinical experience and toxicity of multifield optimization
(MFO) intensity modulated proton therapy (IMPT) for patients with head and neck tumors …

The favorable beam properties of protons can be translated into clinical benefits by target
dose escalation to improve local control without enhancing unacceptable radiation toxicity or …

Objective To externally validate head and neck cancer (HNC) photon-derived normal tissue
complication probability (NTCP) models in patients treated with proton beam therapy (PBT) …

Purpose The purpose of this study was to determine, by treatment plan comparison along
with normal tissue complication probability (NTCP) modeling, whether a subpopulation of …

Opinion statement The application of proton beam radiation therapy in the treatment of head
and neck cancer has grown tremendously in the past few years. Globally, widespread …

Because of its sharp lateral penumbra and steep distal fall-off, proton therapy offers
dosimetric advantages over photon therapy. In head and neck cancer, proton therapy has …