Can better management of periodontal disease delay the onset and progression of Alzheimer's disease?

A Harding, S Robinson, SJ Crean… - Journal of Alzheimer's …, 2017 - content.iospress.com
A risk factor relationship exists between periodontal disease and Alzheimer's disease (AD)
via tooth loss, and improved memory following dental intervention. This links the microbial …

Clinical periodontal variables in patients with and without dementia—a systematic review and meta-analysis

A Maldonado, O Laugisch, W Bürgin, A Sculean… - Clinical oral …, 2018 - Springer
Background Considering the increasing number of elderly people, dementia has gained an
important role in today's society. Although the contributing factors for dementia have not …

Periodontitis and dementia: a bidirectional relationship?

A Harding, SK Singhrao - Journal of Dental Research, 2022 - journals.sagepub.com
Long-standing poor oral hygiene/pathogen load (as reflected by increased pocket depth) is
a likely risk for exacerbating early-onset AD and rapid deterioration in cognition due to …

[HTML][HTML] Unlocking modifiable risk factors for Alzheimer's disease: Does the oral microbiome hold some of the keys?

A Loughman, CJ Adler… - Journal of Alzheimer's …, 2023 - content.iospress.com
Advancing age is recognized as the primary risk factor for Alzheimer's disease (AD);
however approximately one third of dementia cases are attributable to modifiable risk factors …

The effects of LW-AFC on intestinal microbiome in senescence-accelerated mouse prone 8 strain, a mouse model of Alzheimer's disease

J Wang, F Ye, X Cheng, X Zhang, F Liu… - Journal of …, 2016 - content.iospress.com
Microbes have deserved broader attention as causal factors in Alzheimer's disease (AD), a
neurodegenerative disorder. The senescence-accelerated mouse prone 8 (SAMP8) strain, a …

[HTML][HTML] Oral dysbiosis and neurodegenerative diseases: correlations and potential causations

JS Nicholson, KS Landry - Microorganisms, 2022 - mdpi.com
Biofilms are a heterogenous complex community of vegetative cells and extracellular
polymeric substances that can adhere to various surfaces and are responsible for a variety …

Update on the bidirectional link between diabetes and periodontitis

L Salhi, M Reners - Periodontitis: Advances in Experimental Research, 2022 - Springer
Aim: To provide an update on the evidence on the bidirectional relationship between
periodontitis and diabetes. Methods: This narrative review was focused on recent studies …

A review of T helper 17 cell-related cytokines in serum and saliva in periodontitis

N Medara, JC Lenzo, KA Walsh, EC Reynolds… - Cytokine, 2021 - Elsevier
Periodontitis is a chronic inflammatory disease with a complex underlying
immunopathology. Cytokines, as molecular mediators of inflammation, play a role in all …

[HTML][HTML] Periodontal systemic connections-novel associations-a review of the evidence with implications for medical practitioners

B Kalakonda, P Koppolu, K Baroudi… - International Journal of …, 2016 - ncbi.nlm.nih.gov
Periodontal diseases, considered as inflammatory diseases have proved to have a spectrum
of systemic implications. Earliest research has associated periodontal disease with common …

Phenotypes, roles, and modulation of regulatory lymphocytes in periodontitis and its associated systemic diseases

H Zou, N Zhou, Y Huang, A Luo… - Journal of Leukocyte …, 2022 - academic.oup.com
Periodontitis is a common chronic inflammatory disease that can result in tooth loss and
poses a risk to systemic health. Lymphocytes play important roles in periodontitis through …