The Golgi apparatus is an essential organelle constructed by the stacking of flattened
vesicles, that is widely distributed in eukaryotic cells and is dynamically regulated during cell …

Thymoquinone, a monoterpene molecule is chemically known as 2-methyl-5-isopropyl-1, 4-
benzoquinone. It is abundantly present in seeds of Nigella sativa L. that is popularly known …

Cancer is one of the highest prevalent diseases in humans. The chances of surviving cancer
and its prognosis are very dependent on the affected tissue, body location, and stage at …

Abstract Thymoquinone (TQ, 2-methyl-5-isopropyl-1, 4-benzoquinone), a monoterpene
molecule present in Nigella sativa L., has an anti-inflammatory, anti-oxidant, and anti …

Transforming growth factor-beta (TGF-β) is a member of a family of secreted cytokines with
vital biological functions in cells. The abnormal expression of TGF-β signaling is a common …

The cancer is probably the most dreaded disease in both men and women and also major
health problem worldwide. Despite its high prevalence, the exact molecular mechanisms of …

Compelling experimental and clinical evidence supports the notion that cyclooxygenase-2,
the inducible isoform of cyclooxygenase, plays a crucial role in oncogenesis. Clinical and …

Introduction: In the past, clinical studies had demonstrated that aspirin and NSAIDs reduce
the risk of colorectal cancer. After the discovery of selective prostaglandin-endoperoxide …

Cyclooxygenase-2 (COX-2) is an enzyme overexpressed in most types of cancers and has
been used for an excellent targetable biomarker. Celecoxib is an effective inhibitor of COX …

The pro-oncogenic kinase PKCε is overexpressed in human prostate cancer and cooperates
with loss of the tumor suppressor Pten for the development of prostatic adenocarcinoma …