Modifiable factors can influence the risk for Alzheimer's disease (AD) and serve as targets
for intervention; however, the biological mechanisms linking these factors to AD are …

Alcohol is a known carcinogen that may be associated with colorectal cancer. However,
most epidemiologic studies assess alcoholic beverage consumption using self-reported …

Methods: This was an analytic observational study with a cross-sectional research design. It
was conducted from November 2021 to June 2022 with 52 patient tissue samples: these …

Environmental exposures such as cigarette smoking influence health outcomes through
intermediate molecular phenotypes, such as the methylome, transcriptome, and …

Background Colorectal cancer (CRC) is a major cause of cancer-related mortality
worldwide. It is the second leading cause of cancer death in men and women in Brunei …

Colorectal cancer is the third most diagnosed cancer worldwide with an estimated 1.93
million cases diagnosed in 2020. Over the past few decades there has been a dramatic rise …

Demographic, lifestyle and biospecimen-related factors at the time of blood collection can
influence metabolite levels in epidemiological studies. Identifying the major influences on …

The role of androgens in metabolism with respect to sex-specific disease associations is
poorly understood. Therefore, we aimed to provide molecular signatures in plasma and …

Introduction: Myriad roles of mucins in normal tissues have been well documented, including
lubrication of the epithelial surfaces; protection from physical damage; facilitation in cell-cell …

Tobacco research remains a clear priority to improve individual and population health, and
has recently become more complex with emerging combustible and noncombustible …