[HTML][HTML] Research methods and new advances in drug–drug interactions mediated by renal transporters
K Lin, X Kong, X Tao, X Zhai, L Lv, D Dong, S Yang… - Molecules, 2023 - mdpi.com
The kidney is critical in the human body's excretion of drugs and their metabolites. Renal
transporters participate in actively secreting substances from the proximal tubular cells and …
transporters participate in actively secreting substances from the proximal tubular cells and …
[HTML][HTML] 心房颤动患者华法林抗凝治疗初期发生抗凝过度的影响因素研究
范彩霞， 李娇， 魏延津， 郭德群， 刘存飞， 李峥嵘， 邱石 - 中国全科医学, 2024 - chinagp.net
背景心房颤动发病率高, 是引起脑卒中, 心血管疾病及全因死亡的重要危险因素,
而适当的抗凝治疗是预防心房颤动相关性卒中的核心. 华法林仍然是目前主要的抗凝药物 …
而适当的抗凝治疗是预防心房颤动相关性卒中的核心. 华法林仍然是目前主要的抗凝药物 …
Associated factors and safety of the rapidly achieving first therapeutic target of warfarin in hospitalized patients: a retrospective cohort study
W Yang, J Ma, W Hu, H Dai, H Xu - International Journal of Clinical …, 2022 - Springer
Background Warfarin is a commonly used anticoagulant drug in clinical practice. Rapidly
achieving the first therapeutic international normalized ratio (INR) of warfarin may reduce the …
achieving the first therapeutic international normalized ratio (INR) of warfarin may reduce the …
[HTML][HTML] Influence of renal impairment and genetic subtypes on warfarin control in japanese patients
T Tanaka, M Ihara, K Fukuma, H Yamamoto… - Genes, 2021 - mdpi.com
The genotypes of vitamin K epoxide reductase complex 1 (VKORC1) and cytochrome P450
2C9 (CYP2C9) can influence therapeutic warfarin doses. Conversely, nongenetic factors …
2C9 (CYP2C9) can influence therapeutic warfarin doses. Conversely, nongenetic factors …
[HTML][HTML] Acute kidney injury interacts with VKORC1 genotype on initiative warfarin dose among heart surgery recipients: a real-world research
L Xiong, F Yu, W Ge, H Xu - Scientific Reports, 2023 - nature.com
Patients who receive heart valve surgery need anticoagulation prophylaxis to reduce the risk
of thrombosis. Warfarin often is a choice but its dosage varies due to gene and clinical …
of thrombosis. Warfarin often is a choice but its dosage varies due to gene and clinical …
The influence of renal impairment and race on maintenance warfarin dosing in a multi-ethnic Southeast Asian population
O Tan, YH Lau, TSJ Chua, JS Hon… - Proceedings of …, 2024 - journals.sagepub.com
Background Warfarin remains an important anticoagulant in certain patient groups. Though
primarily liver-metabolised, recent research suggests renal function influences warfarin …
primarily liver-metabolised, recent research suggests renal function influences warfarin …
[HTML][HTML] 慢性肾脏病患者口服抗凝药物临床应用的研究进展
杨富蓉， 钱懿轶， 周晓倩， 杨松烨， 陈韦兆… - Advances in Clinical …, 2023 - hanspub.org
慢性肾脏病(chronic kidney disease, CKD) 已然成为一个全球公认的公共卫生问题,
普遍认为CKD 和心脑血管疾病(cerebrovascular disease, CVD) 会互相影响彼此相关的结局 …
普遍认为CKD 和心脑血管疾病(cerebrovascular disease, CVD) 会互相影响彼此相关的结局 …
[HTML][HTML] Influencing Factors of Overanticoagulation at Initial Stage of Warfarin Anticoagulation Therapy in Patients with Atrial Fibrillation
C FAN, J LI, Y WEI, D GUO, C LIU, Z LI… - Chinese General Practice, 2024 - chinagp.net
Background Atrial fibrillation (AF) is an important risk factor for stroke, cardiovascular
disease and all-cause mortality with high prevalence, and appropriate anticoagulant therapy …
disease and all-cause mortality with high prevalence, and appropriate anticoagulant therapy …