BRAF inhibitors in thyroid cancer: clinical impact, mechanisms of resistance and future perspectives
The Kirsten rat sarcoma viral oncogene homolog (RAS)/v-raf-1 murine leukemia viral
oncogene homolog 1 (RAF)/mitogen-activated protein kinase 1 (MAPK) signaling cascade is …
oncogene homolog 1 (RAF)/mitogen-activated protein kinase 1 (MAPK) signaling cascade is …
Role of molecular markers to predict distant metastasis in papillary thyroid carcinoma: Promising value of TERT promoter mutations and insignificant role of BRAF …
HG Vuong, AMA Altibi, UNP Duong, HTT Ngo… - Tumor …, 2017 - journals.sagepub.com
The presence of distant metastasis is associated with an adverse outcome in papillary
thyroid cancer. We performed a meta-analysis to investigate the role of molecular markers …
thyroid cancer. We performed a meta-analysis to investigate the role of molecular markers …
Prevalence, Tumorigenic Role, and Biochemical Implications of Rare BRAF Alterations
S Barollo, R Pezzani, A Cristiani, M Redaelli… - Thyroid, 2014 - liebertpub.com
Background: Papillary thyroid carcinoma (PTC) is the most common malignant tumor of the
thyroid gland, accounting for 74–80% of all thyroid cancers. The 1799T> A transversion is an …
thyroid gland, accounting for 74–80% of all thyroid cancers. The 1799T> A transversion is an …
Expression of miRNAs in Papillary Thyroid Carcinomas Is Associated with BRAF Mutation and Clinicopathological Features in Chinese Patients
Y Sun, S Yu, Y Liu, F Wang, Y Liu… - International Journal of …, 2013 - Wiley Online Library
MicroRNAs (miRNAs) dysregulation has been shown to play a critical regulatory role in
papillary thyroid carcinomas (PTCs). BRAF mutation is associated with poor …
papillary thyroid carcinomas (PTCs). BRAF mutation is associated with poor …
BRAFV600E mutation is associated with aggressive features in papillary thyroid carcinomas ≤ 1.5 cm
JA Silver, M Bogatchenko… - … -Head & Neck …, 2021 - journals.sagepub.com
Background While some studies suggest that the BRAF V600E mutation correlates with a
high-risk phenotype in papillary thyroid microcarcinoma (PTMC), more evidence is …
high-risk phenotype in papillary thyroid microcarcinoma (PTMC), more evidence is …
A combination of immunohistochemistry and molecular approaches improves highly sensitive detection of BRAF mutations in papillary thyroid cancer
C Martinuzzi, L Pastorino, V Andreotti, A Garuti… - Endocrine, 2016 - Springer
The optimal method for BRAF mutation detection remains to be determined despite
advances in molecular detection techniques. The aim of this study was to compare, against …
advances in molecular detection techniques. The aim of this study was to compare, against …
Prognostic factors of papillary and follicular carcinomas in Japan based on data of kuma hospital
Y Ito, A Miyauchi - Journal of thyroid research, 2012 - Wiley Online Library
There are some important prognostic factors for papillary thyroid carcinoma (PTC) and
follicular thyroid carcinoma (FTC). In this paper, clinicopathological features significantly …
follicular thyroid carcinoma (FTC). In this paper, clinicopathological features significantly …
Radiation exposure does not significantly contribute to the risk of recurrence of Chernobyl thyroid cancer
PO Rumyantsev, VA Saenko, AA Ilyin… - The Journal of …, 2011 - academic.oup.com
abstract Context: Papillary thyroid carcinoma (PTC) in patients exposed to environmental
radioiodine after the Chernobyl accident is thought to have a relatively aggressive clinical …
radioiodine after the Chernobyl accident is thought to have a relatively aggressive clinical …
Distinguishing non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) from classic and invasive follicular-variant papillary thyroid …
T Legesse, L Parker, J Heath, PN Staats - Journal of the American Society …, 2019 - Elsevier
Introduction An international panel recently recommended reclassification of non-invasive
follicular variant of papillary thyroid carcinoma (PTC) to non-invasive follicular thyroid …
follicular variant of papillary thyroid carcinoma (PTC) to non-invasive follicular thyroid …
Old and new insights in the treatment of thyroid carcinoma
JM Gasent Blesa, E Grande Pulido… - Journal of Thyroid …, 2010 - Wiley Online Library
Thyroid cancer is the endocrine tumor that bears the highest incidence with 33 550 new
cases per year. It bears an excellent prognosis with a mortality of 1530 patients per year …
cases per year. It bears an excellent prognosis with a mortality of 1530 patients per year …