Postprandial hyperlipidemia, endothelial dysfunction and cardiovascular risk: focus on incretins
S Ansar, J Koska, PD Reaven - Cardiovascular diabetology, 2011 - Springer
Cardiovascular disease (CVD) risk in type 2 diabetes (T2DM) is only partially reduced by
intensive glycemic control. Diabetic dyslipidemia is suggested to be an additional important …
intensive glycemic control. Diabetic dyslipidemia is suggested to be an additional important …
Assessing the comparative effectiveness of newly marketed medications: methodological challenges and implications for drug development
Comparative‐effectiveness research (CER) aims to produce actionable evidence regarding
the effectiveness and safety of medical products and interventions as they are used outside …
the effectiveness and safety of medical products and interventions as they are used outside …
Cardiovascular safety of the dipetidyl peptidase‐4 inhibitor alogliptin in type 2 diabetes mellitus
Aim As there have been concerns that some classes or agents for the treatment of type 2
diabetes may increase CV risk, we evaluated the cardiovascular profile of the dipeptidyl …
diabetes may increase CV risk, we evaluated the cardiovascular profile of the dipeptidyl …
Exenatide extended-release: a review of its use in type 2 diabetes mellitus
LJ Scott - Drugs, 2012 - Springer
Subcutaneous exenatide extended-release (ER; Bydureon™; also known as exenatide
once weekly), a glucagon-like peptide-1 receptor agonist, provides a convenient, simple …
once weekly), a glucagon-like peptide-1 receptor agonist, provides a convenient, simple …
Incretins and preservation of endothelial function
J Koska - Cardiovascular & Hematological Agents in Medicinal …, 2012 - ingentaconnect.com
The endothelium is critical for multiple processes occurring on both sides of the vascular
wall including regulation of blood flow, maintenance of blood fluidity and control of …
wall including regulation of blood flow, maintenance of blood fluidity and control of …
Effect of strict glycemic control in patients with diabetes mellitus on frequency of macrovascular events
A Singh, R Donnino, H Weintraub… - The American journal of …, 2013 - Elsevier
Despite a better understanding of cardiovascular risk factors and attempts at optimal
management, diabetes-related macrovascular events remain a significant cause of morbidity …
management, diabetes-related macrovascular events remain a significant cause of morbidity …
Glucagon-like peptide-1 receptor agonists for the management of diabetic peripheral neuropathy
C Liu, T Wu, N Ren - Frontiers in Endocrinology, 2024 - frontiersin.org
Diabetes mellitus is a prevalent chronic disease characterized by hyperglycemia. Diabetic
peripheral neuropathy (DPN) is one of the complications of diabetes mellitus and is caused …
peripheral neuropathy (DPN) is one of the complications of diabetes mellitus and is caused …
Quantitative systems pharmacology: applications and adoption in drug development
S Ramanujan, K Gadkar, A Kadambi - Systems pharmacology and …, 2016 - Springer
Biopharmaceutical companies have increasingly been exploring Quantitative Systems
Pharmacology (QSP) as a potential avenue to address current challenges in drug …
Pharmacology (QSP) as a potential avenue to address current challenges in drug …
Exenatide extended-release; clinical trials, patient preference, and economic considerations
SA Doggrell - Patient preference and adherence, 2013 - Taylor & Francis
Type 2 diabetes remains an escalating problem worldwide, despite a range of treatments
being available. The revelation that insulin secretion is under the control of a gut hormone …
being available. The revelation that insulin secretion is under the control of a gut hormone …
Impact of treatment with rosuvastatin and atorvastatin on cardiovascular outcomes: evidence from the Archimedes-simulated clinical trials
F Colivicchi, C Sternhufvud… - … and Outcomes Research, 2015 - Taylor & Francis
Objective No clinical trials have been conducted to directly compare the effect of the two
high-intensity statins, rosuvastatin and atorvastatin, on cardiovascular outcomes. However …
high-intensity statins, rosuvastatin and atorvastatin, on cardiovascular outcomes. However …