Chronic pain exerts an enormous personal and economic burden, affecting more than 30%
of people worldwide according to some studies. Unlike acute pain, which carries survival …

The biopsychosocial model of pain dominates the scientific community's understanding of
chronic pain. Indeed, the biopsychosocial approach describes pain and disability as a …

The experience of pain is characterized by tremendous inter-individual variability. Multiple
biological and psychosocial variables contribute to these individual differences in pain …

The high prevalence and societal burden of chronic pain, its undertreatment, and disparities
in its management have contributed to the acknowledgment of chronic pain as a serious …

There is increasing recognition that many if not most common chronic pain conditions are
heterogeneous with a high degree of overlap or coprevalence of other common pain …

Acute and chronic pain complaints, although common, are generally poorly served by
existing therapies. This unmet clinical need reflects a failure to develop novel classes of …

The psychosocial and functional consequences of chronic pain disorders have been well
documented as having significant effects on the experience of pain, presentation to health …

OA is a painful joint disease that predominantly affects the elderly. Pain is the primary
symptom of OA, and it can present as either intermittent or constant. OA pain mechanisms …

The past few decades have witnessed a huge leap forward in our understanding of the
mechanistic underpinnings of pain, in normal states where it helps protect from injury, and …

The special situation brought about by the coronavirus pandemic and the confinement
imposed by the Government, has given rise to numerous changes in working habits. The …