Chronic pain exerts an enormous personal and economic burden, affecting more than 30%
of people worldwide according to some studies. Unlike acute pain, which carries survival …

The biopsychosocial model of pain dominates the scientific community's understanding of
chronic pain. Indeed, the biopsychosocial approach describes pain and disability as a …

It has long been appreciated that individuals differ from each other in important ways. More
than 2000 years ago, Plato said:“No 2 persons are born exactly alike; but each differs from …

There is increasing recognition that many if not most common chronic pain conditions are
heterogeneous with a high degree of overlap or coprevalence of other common pain …

Chronic pain is a common public health problem that has a detrimental impact on patient
health, quality of life (QoL), and function, and poses a substantial socioeconomic burden …

Objective To systematically determine the specific impact of therapeutic alliance (TA) on
chronic musculoskeletal pain, identify factors influencing TA between physical therapists …

The psychosocial and functional consequences of chronic pain disorders have been well
documented as having significant effects on the experience of pain, presentation to health …

Pain reduction is a primary goal of physical therapy for patients who present with acute or
persistent pain conditions. The purpose of this review is to describe a mechanism-based …

OA is a painful joint disease that predominantly affects the elderly. Pain is the primary
symptom of OA, and it can present as either intermittent or constant. OA pain mechanisms …

Acute and chronic pain complaints, although common, are generally poorly served by
existing therapies. This unmet clinical need reflects a failure to develop novel classes of …