Poor bioavailability associated with poorly water-soluble compounds remains a challenging
issue in drug development. Particle engineering may be used to improve the …

Commercial development of nanosuspensions for oral drug delivery generally involves a
drying step which aims to generate a stable product that rapidly releases the nanocrystals …

Objective: Azilsartan medoxomil is considered as a prodrug of the active metabolite,
azilsartan which is an angiotensin II receptor blocker that can be utilized for the treatment of …

Nanomaterials are extensively used for their theranostic applications in the field of infectious
disease. These nanomaterials exhibited improvement in the efficacy of anti-infective agents …

对微通道反溶剂沉淀法制备白藜芦醇(RES) 纳米药物分散体进行了研究. 采用T
型微通道反应器优化操作参数制备RES 纳米分散体, 当RES 溶液与反溶剂水溶液进料流量比为 …

Bioavailability of some hydrophobic bioactive like carotenoids, polyphenols, fat solvent
nutrients, phytosterols (PS), and unsaturated fats are constrained due to their restricted …

The purpose of the study was to use existing methods such as melting point depression and
contact angle methods to predict the suitability of the drug-polymer system for the production …

A novel spontaneous emulsification method using porous polymer particles was
investigated for the facile preparation of emulsions without mechanical manipulation. Porous …

Most of the current NCEs (New chemical entities) in research pipeline belongs to the brick-
dust category of drugs, which faces solubility and dissolution rate limited bioavailability …

Poor bioavailability associated with poorly water-soluble compounds remains a challenging
issue in drug development. Particle engineering may be used to improve the …