Pulmonary fibrosis: Therapeutic and mechanistic insights into the role of phytochemicals
SA Hosseini, F Zahedipour, T Sathyapalan… - …, 2021 - Wiley Online Library
Pulmonary fibrosis (PF) is the devastating consequence of various inflammatory diseases of
the lung. PF leads to a reduction of lung function, respiratory failure, and death. Several …
the lung. PF leads to a reduction of lung function, respiratory failure, and death. Several …
Sirtuins as endogenous regulators of lung fibrosis: a current perspective
S Mazumder, M Barman, U Bandyopadhyay, S Bindu - Life sciences, 2020 - Elsevier
Fibrotic lung diseases qualify among the most dreaded irreversible interstitial pulmonary
complications with progressive yet largely unpredictable clinical course. Idiopathic …
complications with progressive yet largely unpredictable clinical course. Idiopathic …
Sirt1 overexpression improves senescence‐associated pulmonary fibrosis induced by vitamin D deficiency through downregulating IL‐11 transcription
J Zhou, H Chen, Q Wang, S Chen, R Wang… - Aging …, 2022 - Wiley Online Library
Determining the mechanism of senescence‐associated pulmonary fibrosis is crucial for
designing more effective treatments for chronic lung diseases. This study aimed to …
designing more effective treatments for chronic lung diseases. This study aimed to …
[HTML][HTML] Hydrogen sulfide attenuates cigarette smoke-induced airway remodeling by upregulating SIRT1 signaling pathway
R Guan, J Wang, Z Cai, Z Li, L Wang, Y Li, J Xu, D Li… - Redox biology, 2020 - Elsevier
Airway remodeling is one of the characteristics for chronic obstructive pulmonary disease
(COPD). The mechanism underlying airway remodeling is associated with epithelial …
(COPD). The mechanism underlying airway remodeling is associated with epithelial …
Reactive oxygen species drive epigenetic changes in radiation‐induced fibrosis
S Shrishrimal, EA Kosmacek… - … medicine and cellular …, 2019 - Wiley Online Library
Radiation‐induced fibrosis (RIF) develops months to years after initial radiation exposure.
RIF occurs when normal fibroblasts differentiate into myofibroblasts and lay down aberrant …
RIF occurs when normal fibroblasts differentiate into myofibroblasts and lay down aberrant …
Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and highly lethal lung disease
with unknown etiology and poor prognosis. IPF patients die within 2 years after diagnosis …
with unknown etiology and poor prognosis. IPF patients die within 2 years after diagnosis …
[HTML][HTML] Resveratrol extracted from Chinese herbal medicines: A novel therapeutic strategy for lung diseases
B Ma, X Li - Chinese Herbal Medicines, 2020 - Elsevier
Lung diseases and their related complications represent a critical source of morbidity and
mortality globally and have become a research focus in recent years. There are plenty of …
mortality globally and have become a research focus in recent years. There are plenty of …
[HTML][HTML] Mitochondrial network dynamics in pulmonary disease: Bridging the gap between inflammation, oxidative stress, and bioenergetics
MD Pokharel, A Garcia-Flores, D Marciano, MC Franco… - Redox Biology, 2024 - Elsevier
Once thought of in terms of bioenergetics, mitochondria are now widely accepted as both the
orchestrator of cellular health and the gatekeeper of cell death. The pulmonary disease field …
orchestrator of cellular health and the gatekeeper of cell death. The pulmonary disease field …
Activation and overexpression of Sirt1 attenuates lung fibrosis via P300
Z Zeng, S Cheng, H Chen, Q Li, Y Hu, Q Wang… - Biochemical and …, 2017 - Elsevier
Persistent fibroblast activation is a predominant feature of idiopathic pulmonary fibrosis
(IPF), but the transcriptional and epigenetic mechanisms controlling this process are not well …
(IPF), but the transcriptional and epigenetic mechanisms controlling this process are not well …
Piperine attenuates cigarette smoke-induced oxidative stress, lung inflammation, and epithelial–mesenchymal transition by modulating the SIRT1/Nrf2 axis
Piperine (PIP) is a major phytoconstituent in black pepper which is responsible for various
pharmacological actions such as anti-inflammatory, antioxidant, and antitumor activity. To …
pharmacological actions such as anti-inflammatory, antioxidant, and antitumor activity. To …