A novel series of pyrimidine-5-carbonitrile derivatives was designed, synthesized, then
evaluated for their cytotoxic activity as novel anti-cancer with dual EGFRWT/COX-2 …

The combretastatins (cis-stilbenoid molecules) have received significant interest because of
their simple chemical structures, excellent antiproliferative activity, and novel anti-tubulin …

Sulfur‐containing heterocyclic derivatives have been disclosed for binding with a wide
range of cancer‐specific protein targets. Various interesting derivatives of sulfur‐containing …

New thiazole, thiazolopyrimidine, and thiazolotriazine derivatives 3–12 and 14a–f were
synthesized. The newly synthesized analogs were tested for in vitro antitumor activity …

In search for new anticancer candidates, a new series of enamide fluorinated‐Schiff base
derivatives were synthesized and confirmed by spectroscopic techniques as well as …

In the past two decades, targeted cancer therapy has emerged as a novel class of
anticancer therapeutics besides traditional chemotherapy, surgery, and radiotherapy. There …

Design, Synthesis, and Investigation of Cytotoxic Activity of cis-Vinylamide-Linked
Combretastatin Analogues as Potential Antica Page 1 Symmetry 2022, 14, 2088. https://doi.org/10.3390/sym14102088 …