Background Among cardiac arrest survivors, about half remain comatose 72 h following
return of spontaneous circulation (ROSC). Prognostication of poor neurological outcome in …

Objective To determine the clinical feasibility of novel serum biomarkers in out-of-hospital
cardiac arrest (OHCA) patients treated with target temperature management (TTM). Methods …

Background Previous studies have reported high prognostic accuracy of circulating
neurofilament light (NfL) at 24–72 h after out-of-hospital cardiac arrest (OHCA), but …

Importance Blood phosphorylated tau (p-tau) and amyloid-β peptides (Aβ) are promising
peripheral biomarkers of Alzheimer disease (AD) pathology. However, their potential …

Background Serum neuron-specific enolase (NSE) is the only recommended biomarker for
multimodal prognostication in postcardiac arrest patients, but low sensitivity of absolute NSE …

Background Despite the high prevalence of neurological complications and mortality
associated with extracorporeal cardiopulmonary resuscitation (ECPR), neurologically …

Background Limited evidence exists for prognostic performance of biomarkers in patients
resuscitated from out-of-hospital cardiac arrest (OHCA) with extracorporeal CPR (ECPR) …

Background Definition of temporal serum proteome profiles after out-of-hospital cardiac
arrest may identify biological processes associated with severe hypoxia–ischaemia and …

BACKGROUND: Clinical methods to quantify brain injury related to neurosurgery are scarce.
Circulating brain injury biomarkers have recently gained increased interest as new …

Background Neuronal ferroptosis is closely related to the disease of the nervous system,
and the objective of the present study was to recognize and verify the potential ferroptosis …