Gut microbiome, metabolome, host immunity associated with inflammatory bowel disease and intervention of fecal microbiota transplantation

R Wu, R Xiong, Y Li, J Chen, R Yan - Journal of Autoimmunity, 2023 - Elsevier
Gut dysbiosis has been associated with inflammatory bowel disease (IBD), one of the most
common gastrointestinal diseases. The microbial communities play essential roles in host …

Epidemiology of community-acquired and recurrent Clostridioides difficile infection

Y Fu, Y Luo, AM Grinspan - Therapeutic advances in …, 2021 - journals.sagepub.com
Clostridioides difficile infection is a leading cause of healthcare-associated infections with
significant morbidity and mortality. For the past decade, the bulk of infection prevention and …

ECCO guidelines on the prevention, diagnosis, and management of infections in inflammatory bowel disease

T Kucharzik, P Ellul, T Greuter, JF Rahier… - Journal of Crohn's …, 2021 - academic.oup.com
The introduction and broad use of new immunosuppressive agents, including biologic
agents and JAK inhibitors, have revolutionised treatment of inflammatory bowel disease …

ACG clinical guidelines: prevention, diagnosis, and treatment of Clostridioides difficile infections

CR Kelly, M Fischer, JR Allegretti… - Official journal of the …, 2021 - journals.lww.com
Clostridioides difficile infection occurs when the bacterium produces toxin that causes
diarrhea and inflammation of the colon. These guidelines indicate the preferred approach to …

Aktualisierte S3-Leitlinie „Diagnostik und Therapie des Morbus Crohn “der Deutschen Gesellschaft für Gastroenterologie, Verdauungs-und Stoffwechselkrankheiten …

A Sturm, R Atreya, D Bettenworth… - Zeitschrift für …, 2022 - thieme-connect.com
Im Jahr 2019 wurden etwa 25 500 Patient* innen mit M. Crohn im Krankenhaus stationär
behandelt [1]. Meistens tritt die Erkrankung in der Adoleszenz und im jungen …

Depletion of butyrate-producing microbes of the Firmicutes predicts nonresponse to FMT therapy in patients with recurrent Clostridium difficile infection

H Tian, J Cui, C Ye, J Zhao, B Yang, Y Xu, S Ji… - Gut …, 2023 - Taylor & Francis
Approximately 10% of individuals diagnosed with Clostridium difficile infection (CDI) show
the resistance to fecal microbiota transplantation (FMT), with the underlying mechanisms …

Infections due to dysregulated immunity: an emerging complication of cancer immunotherapy

T Morelli, K Fujita, G Redelman-Sidi, PT Elkington - Thorax, 2022 - thorax.bmj.com
Immune checkpoint inhibitors (ICIs) have revolutionised cancer treatment. However, immune-
related adverse events (irAEs) are a common side effect which can mimic infection …

Influence of microbiota on intestinal immune system in ulcerative colitis and its intervention

SL Zhang, SN Wang, CY Miao - Frontiers in immunology, 2017 - frontiersin.org
Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) with chronic and recurrent
characteristics caused by multiple reasons. Although the pathogenic factors have not been …

Risk of common infections in people with inflammatory bowel disease in primary care: a population-based cohort study

PM Irving, S de Lusignan, D Tang… - BMJ open …, 2021 - bmjopengastro.bmj.com
Objective To evaluate the risk of common infections in individuals with inflammatory bowel
disease (IBD)[ulcerative colitis and Crohn's disease] compared with matched controls in a …

A Novel Combination Therapy Using Rosuvastatin and Lactobacillus Combats Dextran Sodium Sulfate-Induced Colitis in High-Fat Diet-Fed Rats by Targeting the …

S Saber, EE Abd El-Fattah, G Yahya, NA Gobba… - Pharmaceuticals, 2021 - mdpi.com
Inflammasome targeting and controlling dysbiosis are promising therapeutic approaches to
control ulcerative colitis. This report is the first to investigate the mechanisms underlying the …