Alzheimer's disease (AD) is a genetically complex, progressive and irreversible
neurodegenerative disorder of the brain which involves multiple associated etiological …

The cellular quality control system degrades abnormal or misfolded proteins and consists of
three different mechanisms: the ubiquitin proteasomal system (UPS), autophagy and …

The prevalence of Alzheimer's disease (AD), a progressive neurodegenerative disorder, is
expected to more than double by 2050. Studies on the pathophysiology of AD have been …

Background Alzheimer's disease (AD) is the most prevalent form of dementia and represents
one of the highest unmet requirements in medicine today. There is shortage of novel …

The amyloid-beta (Aβ) hypothesis that dyshomeostasis between Aβ production and
clearance is a very early, key molecular factor in the etiology of Alzheimer's disease (AD) …

Alzheimer's disease (AD) is an incurable neurodegenerative disease characterised clinically
by learning and memory impairments. Amyloid beta (Aβ) peptide-induced synaptic …

Alzheimer's disease (AD) is the most common neurodegenerative disorder causing
dementia worldwide, and is mainly characterized by aggregated β-amyloid (Aβ). Increasing …

Globally, neurological diseases pose a major burden to healthcare professionals in terms of
the management and prevention of the disorder. Among neurological diseases, Alzheimer's …

Recent evidence suggests that the development of Alzheimer's disease (AD) and related
cognitive loss is due to mutations in the Amyloid Precursor Protein (APP) gene on …

Alzheimer's disease (AD) is a degenerative neurological disorder with incurable
characteristics. To identify the substantial solution, we used a structural biomarker (structural …