Infectious diseases, along with cancers, are among the main causes of death among
humans worldwide. The production of therapeutic proteins for treating diseases at large …

With the ever-increasing global population, it is impossible to meet the demand for animal
protein by relying only on conventional methods due to the depleting natural resources. It is …

The growing biopharmaceutical industry has reached a level of maturity that allows for the
monitoring of numerous key variables for both process characterization and outcome …

The biopharmaceutical market has experienced a tremendous growth in the last years.
However, this growth should be balanced considering the difficulty in bioproduct …

Process intensification strives for more efficient conversion of raw materials into products
while minimizing resource usage. In the biopharma industry, typical intensification gains …

This review focuses on why bio-capacitance has developed to become the standard online
method to estimate biomass in cell-based bio-manufacturing processes. There is now a …

Purpose There is a growing interest in continuous biopharmaceutical processing due to the
advantages of small footprint, increased productivity, consistent product quality, high …

This work aims to evaluate the benefits of the continuous process in biopharmaceutical
manufacturing of monoclonal antibodies (mAbs). An integrated continuous process is …

The goal of cell culture process intensification is to increase volumetric productivity,
generally by increasing viable cell density (VCD), cell specific productivity or production …

Much of the biopharmaceutical industry's success over the past 30 years has relied on
products derived from Chinese Hamster Ovary (CHO) cell lines. During this time …