Venous endothelial function in cardiovascular disease

P Dardi, DEF dos Reis Costa, HCR Assunção… - Bioscience …, 2022 - portlandpress.com
The essential role of the endothelium in vascular homeostasis is associated with the release
of endothelium-dependent relaxing and contractile factors (EDRF and EDCF, respectively) …

Thymoquinone regulates nitric oxide synthase enzymes and receptor-interacting serine-threonine kinases in isoproterenol-induced myocardial infarcted rats

N Deger, R Ozmen, D Karabulut - Chemico-Biological Interactions, 2022 - Elsevier
This study aims to investigate the protective effects of thymoquinone (THQ) in isoproterenol
(ISO)-induced myocardial infarction (MI) in rats. Thirty-two rats were divided into four equal …

miRNA-22 is involved in the aortic reactivity in physiological conditions and mediates obesity-induced perivascular adipose tissue dysfunction

CS Balbino-Silva, GK Couto, CA Lino… - Life Sciences, 2023 - Elsevier
Aims Blood vessels are surrounded by perivascular adipose tissue (PVAT), which plays an
important role in vascular tonus regulation due to its anticontractile effect; however, this …

Vena cava presents endothelial dysfunction prior to thoracic aorta in heart failure: the pivotal role of nNOS uncoupling/oxidative stress

P Dardi, LR Perazza, GK Couto, GP Campos… - Clinical …, 2021 - portlandpress.com
Arterial endothelial dysfunction has been extensively studied in heart failure (HF). However,
little is known about the adjustments shown by the venous system in this condition …

Combined effects of nitric oxide synthase 3 genetic variant and childhood emotional abuse on earlier onset of suicidal behaviours

A Lengvenyte, A Sundaresh, R Strumila… - Progress in neuro …, 2022 - Elsevier
Marked heterogeneity in suicide attempters has been observed, with earlier onset being
linked to stronger heritability, more childhood maltreatment. Nitric oxide signalling system …

O tratamento com apocinina previne a disfunção endotelial ao melhorar a função das caveolas em aortas de ratos espontaneamente hipertensos (SHR)

MSQ Silva - 2023 - repositorio.unesp.br
O menor número e a função prejudicada das cavéolas em células endoteliais de artérias de
SHR tem sido associado à disfunção endotelial e hipertensão. O tratamento com Apocinina …