[HTML][HTML] Ubiquitin-specific proteases (USPs) and metabolic disorders

H Kitamura - International journal of molecular sciences, 2023 - mdpi.com
Ubiquitination and deubiquitination are reversible processes that modify the characteristics
of target proteins, including stability, intracellular localization, and enzymatic activity …

[HTML][HTML] Sex-specific changes in metabolism during the transition from chow to high-fat diet feeding are abolished in response to dieting in C57BL/6J mice

J Oraha, RF Enriquez, H Herzog, NJ Lee - International Journal of …, 2022 - nature.com
Abstract Background/Objective Female mice are often excluded from diet-induced obesity
studies as they are more resistant to the obesifying effects of a high-fat diet (HFD). However …

VDR activation attenuates osteoblastic ferroptosis and senescence by stimulating the Nrf2/GPX4 pathway in age-related osteoporosis

P Xu, B Lin, X Deng, K Huang, Y Zhang… - Free Radical Biology and …, 2022 - Elsevier
Ferroptosis plays an essential role in the pathology of osteoporosis. This study investigated
whether vitamin D receptor (VDR) activation could protect against age-related osteoporosis …

[HTML][HTML] 基于HS-SPME-GC-MS 和OPLS-DA 模型探究不同嫩度驴肉的关键挥发性物质成分差异

李武峰, 邱丽霞, 关家伟, 李丽, 杜敏 - 畜牧兽医学报, 2022 - xml-data.org
旨在检测驴肉挥发性物质成分, 探究与广灵驴嫩度相关的关键差异风味物质并解析关键挥发性
物质与嫩度基因之间的功能与联系. 本研究选用30 头生长环境和饲养条件相同 …

[HTML][HTML] Oxidative Stress in Postbariatric Patients: A Systematic Literature Review Exploring the Long-term Effects of Bariatric Surgery

JJ Pradel-Mora, G Marín… - … Surgery–Global Open, 2024 - journals.lww.com
Background: The present study investigates the impact of oxidative stress after bariatric
surgery in patients with obesity. This field of study has gained great interest in recent years …

Understanding myoblast differentiation pathways when cultured on electroactive scaffolds through proteomic analysis

S Ribeiro, C Ribeiro, VM Martins… - … applied materials & …, 2022 - ACS Publications
Electroactive materials allow the modulation of cell–materials interactions and cell fate,
leading to advanced tissue regeneration strategies. Nevertheless, their effect at the cellular …

[HTML][HTML] Identification of novel gene signatures and immune cell infiltration in intervertebral disc degeneration using bioinformatics analysis

T Tang, Z He, Z Zhu, F Wang, H Chen… - Frontiers in Molecular …, 2023 - frontiersin.org
Background: Intervertebral disc degeneration (IDD) is the leading cause of lower back pain,
and an overall understanding of the molecular mechanisms related to IDD is still lacking …

Differential effects of Western diet and traumatic muscle injury on skeletal muscle metabolic regulation in male and female mice

J Heo, AG Schifino… - Journal of Cachexia …, 2023 - Wiley Online Library
Background This study was designed to develop an understanding of the pathophysiology
of traumatic muscle injury in the context of Western diet (WD; high fat and high sugar) and …

[HTML][HTML] T2DB: A web database for long non-coding RNA genes in type II diabetes

R Distefano, M Ilieva, JH Madsen, H Ishii, M Aikawa… - Non-coding RNA, 2023 - mdpi.com
Type II diabetes (T2D) is a growing health problem worldwide due to increased levels of
obesity and can lead to other life-threatening diseases, such as cardiovascular and kidney …

[HTML][HTML] Brain sex-dependent alterations after prolonged high fat diet exposure in mice

V Murtaj, S Penati, S Belloli, M Foti, A Coliva… - Communications …, 2022 - nature.com
We examined effects of exposing female and male mice for 33 weeks to 45% or 60% high fat
diet (HFD). Males fed with either diet were more vulnerable than females, displaying higher …