Allostery is the mechanism by which information and control are propagated in
biomolecules. It regulates ligand binding, chemical reactions, and conformational changes …

Transient receptor potential (TRP) channels are a large and diverse family of
transmembrane ion channels that are widely expressed, have important physiological roles …

Cannabidiol is popularly known as CBD, a substance that is part of the cannabinoids,
chemical components extracted from the cannabis or hemp plant. Of all the chemical …

TRP channels are important pharmacological targets in physiopathology. TRPV2 plays
distinct roles in cardiac and neuromuscular function, immunity, and metabolism, and is …

Transient receptor potential (TRP) ion channels are involved in the surveillance or
regulation of the acid-base balance. Here, we demonstrate that weak carbonic acids …

Transient receptor potential melastatin 2 (TRPM2) is a non-selective cation channel that
exhibits Ca2+ permeability. The TRPM2 channel is expressed in various tissues and cells …

Ion channels establish the voltage gradient across cellular membranes by providing
aqueous pathways for ions to selectively diffuse down their concentration gradients. The …

Cannabis sativa has long been used for neurological and psychological healing. Recently,
cannabidiol (CBD) extracted from cannabis sativa has gained prominence in the medical …

Introduction The endocannabinoid (eCB) system is named after the discovery that
endogenous cannabinoids bind to the same receptors as the phytochemical compounds …

People use cannabidiol (CBD), the primary non-psychoactive cannabinoid of cannabis, as a
treatment for symptoms that are commonly associated with pregnancy including nausea …