Biologically active isoquinoline alkaloids covering 2014–2018
XF Shang, CJ Yang… - Medicinal research …, 2020 - Wiley Online Library
Isoquinoline alkaloids, an important class of N‐based heterocyclic compounds, have
attracted considerable attention from researchers worldwide since the early 19th century …
attracted considerable attention from researchers worldwide since the early 19th century …
Discovery of natural anti-inflammatory alkaloids: Potential leads for the drug discovery for the treatment of inflammation
Inflammation is an adaptive response of the immune system to tissue malfunction or
homeostatic imbalance. Corticosteroids and non-steroidal anti-inflammatory drugs (NSAIDs) …
homeostatic imbalance. Corticosteroids and non-steroidal anti-inflammatory drugs (NSAIDs) …
Advances in research of spirodienone and its derivatives: Biological activities and synthesis methods
C Chen, L He - European Journal of Medicinal Chemistry, 2020 - Elsevier
Spirodienone derivatives have unique structural characteristics. Its spiroatoms are
quaternary carbons that act as bridges between dienone and four, five, six and even seven …
quaternary carbons that act as bridges between dienone and four, five, six and even seven …
Rapid profiling of alkaloid analogues in Sinomenii Caulis by an integrated characterization strategy and quantitative analysis
ZM Jiang, L Wang, H Pang, Y Guo, PT Xiao… - … of Pharmaceutical and …, 2019 - Elsevier
Alkaloids, the principal constituents in the caulis of Sinomenium acutum, have gained an
increasing interest over the past decades since they are widely employed as a clinical …
increasing interest over the past decades since they are widely employed as a clinical …
Eleven undescribed alkaloids from the rhizomes of Sinomenium acutum and their Ido1 and TDO inhibitory activities
R Bi, XN Yang, HF Zhou, LY Peng, JX Liu, QS Zhao - Phytochemistry, 2022 - Elsevier
Eleven previously undescribed alkaloids, named sinometumines AK, along with three
known alkaloids, were isolated from the rhizomes of Sinomenium acutum. The chemical …
known alkaloids, were isolated from the rhizomes of Sinomenium acutum. The chemical …
Varying light intensity can alter metabolic profile and cannabispiradienone content of industrial hemp
M Li, M Roman, J Yuan, M Rehman, L Liu - Industrial Crops and Products, 2023 - Elsevier
Industrial hemp (Cannabis sativa L.) is an economic crop with high yield and stress
resistance. Hemp metabolites have high medicinal value and development potential, which …
resistance. Hemp metabolites have high medicinal value and development potential, which …
New analogues of aporphine alkaloids
YC Ge, KW Wang - Mini reviews in medicinal chemistry, 2018 - ingentaconnect.com
Aporphine alkaloids, characterized by a heterocyclic aromatic basic skeleton, are known
from different organisms and exhibit various biological activities: anti-tumor, anti-viral, anti …
from different organisms and exhibit various biological activities: anti-tumor, anti-viral, anti …
In Vitro and In Silico Evaluation of Cholinesterase Inhibition by Alkaloids Obtained from Branches of Abuta panurensis Eichler
R da Silva Mesquita, A Kyrylchuk, A Cherednichenko… - Molecules, 2022 - mdpi.com
Alkaloids are natural products known as ethnobotanicals that have attracted increasing
attention due to a wide range of their pharmacological properties. In this study …
attention due to a wide range of their pharmacological properties. In this study …
Spiroligustolides A and B: Two pairs of enantiomeric spiro-orthoester-containing phthalide dimers as Cav3. 1 calcium channel inhibitors from Ligusticum Chuanxiong …
LY Wang, WY Li, HF Zhou, XY Zhao, XN Li, XD Wu… - Bioorganic …, 2022 - Elsevier
Two pairs of unprecedented enantiomeric phthalide dimers, spiroligustolides A (1a/1b) and
B (2a/2b), featuring a unique spiroorthoster linkage between two monomeric units to form a …
B (2a/2b), featuring a unique spiroorthoster linkage between two monomeric units to form a …
N-Chloroformylimidazolidinone Enolates as 1,3-Dipolar Reagents for the Stereoselective Synthesis of 3,4-Dihydroisoquinolones
H Abas, MM Amer, O Olaizola, J Clayden - Organic letters, 2019 - ACS Publications
N-Chloroformyl imidazolidinone derivatives of enantiopure amino acids may be
deprotonated to give remarkably well-behaved enolates with both nucleophilic and …
deprotonated to give remarkably well-behaved enolates with both nucleophilic and …