Neutrophils are major effectors and regulators of the immune system. They play critical roles
not only in the eradication of pathogens but also in cancer initiation and progression …

Neutrophil Extracellular Traps (NETs) are net-like structures composed of DNA-histone
complexes and proteins released by activated neutrophils. In addition to their key role in the …

Neutrophils are an absolutely essential part of the innate immune system, playing an
essential role in the control of infectious diseases but more recently are also being viewed …

In human pathophysiology, the clash between microbial infection and host immunity
contributes to multiple diseases. Cystic fibrosis (CF) is a classical example of this …

Neutrophils or polymorphonuclear leukocytes (PMN) are key participants in the innate
immune response for their ability to execute different effector functions. These cells express …

Inflammation plays a critical role in cystic fibrosis (CF) lung pathology and disease
progression making it an active area of research and important therapeutic target. In this …

Mucosal surfaces are lined by epithelial cells, which provide a complex and adaptive
module that ensures first-line defense against external toxics, irritants, antigens, and …

Invasive Staphylococcus aureus infections are a leading cause of morbidity and mortality in
both hospital and community settings, especially with the widespread emergence of virulent …

Cutaneous fibrosis results from suboptimal wound healing following significant tissue injury
such as severe burns, trauma, and major surgeries. Pathologic skin fibrosis results in scars …

Abstract Background and Aims In ulcerative colitis [UC], mucosal damage occurs in areas
that are infiltrated with neutrophils. The antimicrobial function of neutrophils relies in part on …