The pharmacological efficacy of baicalin in inflammatory diseases

Y Wen, Y Wang, C Zhao, B Zhao, J Wang - International Journal of …, 2023 - mdpi.com
Baicalin is one of the most abundant flavonoids found in the dried roots of Scutellaria
baicalensis Georgi (SBG) belonging to the genus Scutellaria. While baicalin is demonstrated …

Reactive oxygen species mediated apoptotic death of colon cancer cells: Therapeutic potential of plant derived alkaloids

VK Nelson, MV Nuli, J Mastanaiah… - Frontiers in …, 2023 - frontiersin.org
Colorectal cancer (CRC) is one of the most deaths causing diseases worldwide. Several risk
factors including hormones like insulin and insulin like growth factors (eg, IGF-1) have been …

Development of pegylated nano‐phytosome formulation with oleuropein and rutin to compare anti‐colonic cancer activity with Olea europaea leaves extract

TH Mahmood, A Al‐Samydai, MA Sulaibi… - Chemistry & …, 2023 - Wiley Online Library
Olive leaf extract is a valuable source of phenolic compounds; primarily, oleuropein (major
component) and rutin. This natural olive leaf extract has potential use as a therapeutic agent …

Capsaicin: A chili pepper bioactive phytocompound with a potential role in suppressing cancer development and progression

A Mondal, S Banerjee, W Terang… - Phytotherapy …, 2024 - Wiley Online Library
Cancer profoundly influences morbidity and fatality rates worldwide. Patients often have
dismal prognoses despite recent improvements in cancer therapy regimens. However …

Signaling pathways driving ocular malignancies and their targeting by bioactive phytochemicals

CR Croley, J Pumarol, BE Delgadillo, AC Cook… - Pharmacology & …, 2023 - Elsevier
Ocular cancers represent a rare pathology. The American Cancer Society estimates that
3,360 cases of ocular cancer occur annually in the United States. The major types of cancers …

Comparison of Phytochemical Composition and Untargeted Metabolomic Analysis of an Extract from Cnidoscolus Aconitifolius (Mill.) II Johnst and Porophyllum …

ÁF Vargas-Madriz, I Luzardo-Ocampo, U Moreno-Celis… - Plants, 2023 - mdpi.com
Cnidoscolus aconitifolius (CA) and Porophyllum ruderale (PR) are representative edible
plants that are a traditional food source in Mexico. This research aimed to analyze the …

Cellular and molecular mechanisms underlying the potential of betulinic acid in cancer prevention and treatment

S Banerjee, S Banerjee, A Bishayee, MN Da Silva… - Phytomedicine, 2024 - Elsevier
Background Betulinic acid (BA), which is a pentacyclic triterpenoid found in the bark of
plane, birch, and eucalyptus trees, has emerged as a compound of significant interest in …

Vitexicarpin suppresses malignant progression of colorectal cancer through affecting c-Myc ubiquitination by targeting IMPDH2

XJ Ding, XM Cai, QQ Wang, N Liu, WL Zhong, XN Xi… - Phytomedicine, 2024 - Elsevier
Background Colorectal cancer (CRC) is the second most common cause of cancer-related
mortality and is characterised by extensive invasive and metastatic potential. Previous …

Antiproliferative Effect of Gallic Acid is Mediated via Mitochondrial‐or ER‐Stress‐Induced Apoptosis and Canonical Autophagy in HT‐29 Cells

J Shao, L Yang, Z Jin, Y Bao, J He, QH Le… - Journal of …, 2024 - Wiley Online Library
Cancer is a noncommunicable disease burden and the second‐leading cause of death
worldwide. Novel medications and drug possibilities are sought everyday throughout the …

[HTML][HTML] Cetuximab-conjugated andrographolide loaded chitosan-pectin composite nanoparticles for colorectal cancer

J Balakarthikeyan, V Mayakrishnan… - Journal of King Saud …, 2024 - Elsevier
The target specificity of drug-loaded nanoparticles can be increased by coating them with
ligands that can bind to the target receptors overexpressed on the surface of cancer cells …