Astragalus polysaccharide: a review of its immunomodulatory effect

C Li, Y Liu, Y Zhang, J Li, J Lai - Archives of Pharmacal Research, 2022 - Springer
The Astragalus polysaccharide is an important bioactive component derived from the dry
root of Astragalus membranaceus. This review aims to provide a comprehensive overview of …

The interaction between nanoparticles and immune system: application in the treatment of inflammatory diseases

J Liu, Z Liu, Y Pang, H Zhou - Journal of Nanobiotechnology, 2022 - Springer
Nanoparticle (NP) is an emerging tool applied in the biomedical field. With combination of
different materials and adjustment of their physical and chemical properties, nanoparticles …

Harnessing and enhancing macrophage phagocytosis for cancer therapy

S Chen, SWT Lai, CE Brown, M Feng - Frontiers in Immunology, 2021 - frontiersin.org
Cancer immunotherapy has revolutionized the paradigm for the clinical management of
cancer. While FDA-approved cancer immunotherapies thus far mainly exploit the adaptive …

Nanotechnology‐based targeted drug delivery: an emerging tool to overcome tuberculosis

Z Baranyai, H Soria‐Carrera, M Alleva… - Advanced …, 2021 - Wiley Online Library
The appearance and rapid spread of drug resistant strains of tuberculosis (TB), one of the
deadliest infectious diseases, pose a serious threat to public health and increase the need …

Nanomedicine-combined immunotherapy for cancer

S Huang, Q Zhao - Current medicinal chemistry, 2020 - ingentaconnect.com
Background: Immunotherapy for cancer includes Chimeric Antigen Receptor (CAR)-T cells,
CAR-natural Killer (NK) cells, PD1, and the PD-L1 inhibitor. However, the proportion of …

Active nano-targeting of macrophages

N Gaspar, G Zambito, CMWG Löwik… - Current …, 2019 - ingentaconnect.com
Macrophages play a role in almost every disease such as cancer, infections, injuries,
metabolic and inflammatory diseases and are becoming an attractive therapeutic target …

Embracing nanomaterials' interactions with the innate immune system

AJP Teunissen, ME Burnett, G Prévot… - Wiley …, 2021 - Wiley Online Library
Immunotherapy has firmly established itself as a compelling avenue for treating disease.
Although many clinically approved immunotherapeutics engage the adaptive immune …

Monocyte (THP-1) Response to Silver Nanoparticles Synthesized with Rumex hymenosepalus Root Extract

FJ Alvarez-Cirerol, JM Galván-Moroyoqui… - Nanomaterials, 2024 - mdpi.com
The study, synthesis, and application of nanomaterials in medicine have grown
exponentially in recent years. An example of this is the understanding of how nanomaterials …

Tumor‑associated macrophages: Role in the pathological process of tumorigenesis and prospective therapeutic use

OV Zhukova, TF Kovaleva… - Biomedical …, 2020 - spandidos-publications.com
The aim of the present study was to evaluate the current body of knowledge regarding tumor‑
associated macrophages (TAMs) and their potential use in antitumor therapy, based on their …

Potential health risks of nanomaterials in food: a methodology to identify signals and prioritise risks

W Brand, PCE Van Kesteren, AG Oomen - 2020 - rivm.openrepository.com
Thanks to nanotechnology, an abundance of new products and nanomaterials for food can
be developed. Nano-iron, for example, could be added to foods to fight anaemia and nano …