Genomic and histopathological tissue biomarkers that predict radiotherapy response in localised prostate cancer

A Wilkins, D Dearnaley… - BioMed Research …, 2015 - Wiley Online Library
Localised prostate cancer, in particular, intermediate risk disease, has varied survival
outcomes that cannot be predicted accurately using current clinical risk factors. External …

Cervical cancer: are there potential new targets? An update on preclinical and clinical results

F Tomao, C Di Tucci, L Imperiale… - Current drug …, 2014 - ingentaconnect.com
According to international guidelines, treatment of cervical cancer (CC) consists of surgery in
early stages and of chemoradiation in locally advanced disease. Metastatic disease is …

[HTML][HTML] Celecoxib mitigates genotoxicity induced by ionizing radiation in human blood lymphocytes

SJ Hosseinimehr, M Fathi, A Ghasemi… - Research in …, 2017 - journals.lww.com
Ionizing radiation causes DNA damage and chromosome abbreviations on normal cells.
The radioprotective effect of celecoxib (CLX) was investigated against genotoxicity induced …

[PDF][PDF] Celecoxib inhibits cell growth and modulates the expression of matrix metalloproteinases in human osteosarcoma MG-63 cell line.

X Zhou, X Shi, K Ren, GT Fan, SJ Wu… - European Review for …, 2015 - europeanreview.org
OBJECTIVE: The goal of this study was to determine the effect of celecoxib, a selective COX-
2 inhibitor, on the growth inhibition of osteosarcoma and its potential anticancer …

[HTML][HTML] Expression and clinical significance of cyclooxygenase 2 and survivin in human gliomas

F Zhang, J Chu, F Wang - Oncology Letters, 2017 - spandidos-publications.com
The present study aimed to determine cyclooxygenase 2 (COX-2) and survivin expression
levels in glioma tissues, and to investigate their association with clinicopathological factors …

[HTML][HTML] Celecoxib can suppress expression of genes associated with PGE2 pathway in chondrocytes under inflammatory conditions

TW Sun, ZH Wu, XS Weng - International Journal of Clinical and …, 2015 - ncbi.nlm.nih.gov
This study aimed to investigate the effect of a selective cyclooxygenase-2 (COX-2) inhibitor
(celecoxib) on the expression of arachidonate-associated inflammatory genes in cultured …

A tissue biomarker–based model that identifies patients with a high risk of distant metastasis and differential survival by length of androgen deprivation therapy in …

A Pollack, JJ Dignam, DA Diaz, Q Wu, R Stoyanova… - Clinical cancer …, 2014 - AACR
Purpose: To examine the relationship between the expression of 7 promising apoptotic/cell
proliferation proteins (Ki-67, p53, MDM2, bcl-2, bax, p16, and Cox-2) and risk of distant …

[PDF][PDF] 直肠癌HIF-1α 和COX-2 的表达与新辅助放化疗敏感性的相关性

徐昶, 宋华羽, 左志贵, 厉金雷, 蔡剑辉, 吴祥斌 - 温州医科大学学报, 2014 - xb.wmu.edu.cn
Objective: To observe the early characteristics of systemic lupus erythematosus (SLE)
patients with retinal vascular lesions and to investigate correlation between the degree of …

辐射对人胶质瘤U251 细胞COX-2 和survivin 表达的影响

储进锦, 张帆, 王凡 - 安徽医药, 2015 - ahyyzz.cn
目的研究辐射对人胶质瘤U251 细胞COX-2 和survivin 蛋白表达的影响. 方法体外培养人胶质瘤
U251 细胞, 随机分为实验组和对照组, 实验组经过10 Gy 剂量X 线照射, 对照组无特殊处理 …

[引用][C] 环氧合酶2 与肿瘤研究进展

李杰, 杨红, 郝洪岭 - 临床误诊误治, 2012