Aerobic gram-negative bacilli, including the family of Enterobacteriaceae and non-lactose
fermenting bacteria such as Pseudomonas and Acinetobacter species, are major causes of …

Introduction The aims of this study were to explore the incidence of in-hospital inappropriate
empiric antibiotic use in patients with severe infection and to identify its relationship with …

Background: Previous evidence-based guidelines on the management of intra-abdominal
infection (IAI) were published by the Surgical Infection Society (SIS) in 1992, 2002, and …

Importance Eravacycline is a novel, fully synthetic fluorocycline antibiotic of the tetracycline
class with in vitro activity against clinically important gram-negative, gram-positive aerobic …

Objectives The objectives of this study were to prospectively assess the rectal carriage rate
of third-generation cephalosporin-resistant Enterobacteriaceae (3GCREB) in non-ICU …

Background: The prevalence of extended-spectrum β-lactamase producing
Enterobacteriaceae (ESBL-E) is increasing worldwide. ESBL-E are known to colonize …

Background Antibiotic-resistant infections have high rates of morbidity and mortality, and
exposure to antibiotics is the crucial risk factor for development of antibiotic resistance. If …

Introduction Bloodstream infections are associated with high mortality rates and contribute
substantially to healthcare costs, but a consensus on the prognostic benefits of appropriate …

An important concern of antibiotic stewardship programs is the selection of empiric antibiotic
therapy for sepsis in the hospitalized patient. 1–5 Although the definition of sepsis continues …

Background. To prevent inappropriate empiric antibiotic treatment in patients with
bacteremia caused by third-generation cephalosporin (3GC)–resistant Enterobacteriaceae …