Social determinants of health (SDoH), which encompass the economic, social,
environmental, and psychosocial factors that influence health, play a significant role in the …

Dopamine regulates reward-related behavior through the mesolimbic dopaminergic
pathway. Stress affects dopamine levels and dopaminergic neuronal activity in the …

Adverse childhood experiences (ACEs) can become biologically embedded leaving a
lasting signature on multiple body systems. ACE scores have been used to associate …

Although there is little direct evidence supporting that stress affects cancer incidence, it does
influence the evolution, dissemination and therapeutic outcomes of neoplasia, as shown in …

Sex/gender effects have been demonstrated for multiple aspects of addiction, with one of the
most commonly cited examples being the “telescoping effect” where women meet criteria …

Epigenetic factors modify the effects of environmental factors on biological outcomes.
Identification of epigenetic changes that associate with PTSD is therefore a crucial step in …

Converging evidence from both animal and human studies have implicated hedonic eating
as a driver of both binge eating and obesity. The construct of food addiction has been used …

The role of stress, trauma, and adversity particularly early in life has been identified as a
contributing factor in both drug and food addictions. While links between traumatic stress …

While it is well known from numerous epidemiologic investigations that social determinants
(socioeconomic, environmental, and psychosocial factors exposed to over the life-course) …

While popular belief harbors little doubt that perceived stress can cause hair loss and
premature graying, the scientific evidence for this is arguably much thinner. Here, we …