The European Alliance of Associations for Rheumatology recently defined difficult to treat
(D2T) rheumatoid arthritis (RA) and provided points to consider in its management. This …

Over the past several decades, the treatment of rheumatoid arthritis (RA) has advanced
significantly, and clinical, structural, and functional remission are achievable therapeutic …

Objective To develop evidence-based European Alliance of Associations for Rheumatology
(EULAR) points to consider (PtCs) for the management of difficult-to-treat rheumatoid …

Objectives Treatment of difficult-to-treat (D2T) RA patients is generally based on trial-and-
error and can be challenging due to a myriad of contributing factors. We aimed to identify …

Although the management of rheumatoid arthritis (RA) has improved remarkably with new
pharmacological therapies, there is still a significant part of patients not reaching treatment …

Abstract Purpose of Review Chronic pain is highly prevalent in patients with rheumatoid
arthritis (RA) and can cause various physical and psychological impairments. Unfortunately …

Difficult-to-treat rheumatoid arthritis is a heterogeneous term in which patients may present
with difficulties in their management for different reasons. This can ultimately lead to patients …

Background The new concept of difficult-to-treat rheumatoid arthritis (D2T RA) refers to RA
patients who remain symptomatic after several lines of treatment, resulting in a high patient …

Backgrounds Treatment of difficult-to-treat rheumatoid arthritis (D2T RA) is one of the
greatest unmet needs in rheumatology. This study aims to find out preferable treatment …

Rheumatoid arthritis (RA) is a long-term disorder that significantly impairs somatic,
emotional, and psychological functioning. The objective of this review is to identify, appraise …